Yu Q - Search Results

1

EZH2-mediated inactivation of IFN-γ-JAK-STAT1 signaling is an effective therapeutic target in MYC-driven prostate cancer.

Wee ZN, Li Z, Lee PL, Lee ST, Lim YP, Yu Q. Wee ZN, et al. Among authors: yu q. Cell Rep. 2014 Jul 10;8(1):204-16. doi: 10.1016/j.celrep.2014.05.045. Epub 2014 Jun 19. Cell Rep. 2014. PMID: 24953652 Free article.

2

Restoring p53-mediated apoptosis in cancer cells: new opportunities for cancer therapy.

Yu Q. Yu Q. Drug Resist Updat. 2006 Feb-Apr;9(1-2):19-25. doi: 10.1016/j.drup.2006.03.001. Drug Resist Updat. 2006. PMID: 16600668 Review.

3

c-Myc overexpression sensitizes Bim-mediated Bax activation for apoptosis induced by histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA) through regulating Bcl-2/Bcl-xL expression.

Jiang X, Tsang YH, Yu Q. Jiang X, et al. Among authors: yu q. Int J Biochem Cell Biol. 2007;39(5):1016-25. doi: 10.1016/j.biocel.2007.01.024. Epub 2007 Feb 2. Int J Biochem Cell Biol. 2007. PMID: 17331788

4

Pharmacologic disruption of Polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells.

Tan J, Yang X, Zhuang L, Jiang X, Chen W, Lee PL, Karuturi RK, Tan PB, Liu ET, Yu Q. Tan J, et al. Among authors: yu q. Genes Dev. 2007 May 1;21(9):1050-63. doi: 10.1101/gad.1524107. Epub 2007 Apr 16. Genes Dev. 2007. PMID: 17437993 Free PMC article.

5

Ribosomal protein S27-like, a p53-inducible modulator of cell fate in response to genotoxic stress.

Li J, Tan J, Zhuang L, Banerjee B, Yang X, Chau JF, Lee PL, Hande MP, Li B, Yu Q. Li J, et al. Among authors: yu q. Cancer Res. 2007 Dec 1;67(23):11317-26. doi: 10.1158/0008-5472.CAN-07-1088. Cancer Res. 2007. PMID: 18056458

6

DACT3 is an epigenetic regulator of Wnt/beta-catenin signaling in colorectal cancer and is a therapeutic target of histone modifications.

Jiang X, Tan J, Li J, Kivimäe S, Yang X, Zhuang L, Lee PL, Chan MT, Stanton LW, Liu ET, Cheyette BN, Yu Q. Jiang X, et al. Among authors: yu q. Cancer Cell. 2008 Jun;13(6):529-41. doi: 10.1016/j.ccr.2008.04.019. Cancer Cell. 2008. PMID: 18538736 Free PMC article.

7

CDKN1C (p57) is a direct target of EZH2 and suppressed by multiple epigenetic mechanisms in breast cancer cells.

Yang X, Karuturi RK, Sun F, Aau M, Yu K, Shao R, Miller LD, Tan PB, Yu Q. Yang X, et al. Among authors: yu q, yu k. PLoS One. 2009;4(4):e5011. doi: 10.1371/journal.pone.0005011. Epub 2009 Apr 2. PLoS One. 2009. PMID: 19340297 Free PMC article.

8

miR-449a and miR-449b are direct transcriptional targets of E2F1 and negatively regulate pRb-E2F1 activity through a feedback loop by targeting CDK6 and CDC25A.

Yang X, Feng M, Jiang X, Wu Z, Li Z, Aau M, Yu Q. Yang X, et al. Among authors: yu q. Genes Dev. 2009 Oct 15;23(20):2388-93. doi: 10.1101/gad.1819009. Genes Dev. 2009. PMID: 19833767 Free PMC article.

9

Combinatorial pharmacologic approaches target EZH2-mediated gene repression in breast cancer cells.

Sun F, Chan E, Wu Z, Yang X, Marquez VE, Yu Q. Sun F, et al. Among authors: yu q. Mol Cancer Ther. 2009 Dec;8(12):3191-202. doi: 10.1158/1535-7163.MCT-09-0479. Mol Cancer Ther. 2009. PMID: 19934278 Free PMC article.

10

E2F1-mediated apoptosis as a target of cancer therapy.

Wu Z, Yu Q. Wu Z, et al. Among authors: yu q. Curr Mol Pharmacol. 2009 Jun;2(2):149-60. doi: 10.2174/1874467210902020149. Curr Mol Pharmacol. 2009. PMID: 20021455 Review.

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