Laiho M - Search Results

1

DNA intercalator BMH-21 inhibits RNA polymerase I independent of DNA damage response.

Colis L, Peltonen K, Sirajuddin P, Liu H, Sanders S, Ernst G, Barrow JC, Laiho M. Colis L, et al. Among authors: laiho m. Oncotarget. 2014 Jun 30;5(12):4361-9. doi: 10.18632/oncotarget.2020. Oncotarget. 2014. PMID: 24952786 Free PMC article.

2

Redox state of tumor suppressor p53 regulates its sequence-specific DNA binding in DNA-damaged cells by cysteine 277.

Buzek J, Latonen L, Kurki S, Peltonen K, Laiho M. Buzek J, et al. Among authors: laiho m. Nucleic Acids Res. 2002 Jun 1;30(11):2340-8. doi: 10.1093/nar/30.11.2340. Nucleic Acids Res. 2002. PMID: 12034820 Free PMC article.

3

Nucleolar protein NPM interacts with HDM2 and protects tumor suppressor protein p53 from HDM2-mediated degradation.

Kurki S, Peltonen K, Latonen L, Kiviharju TM, Ojala PM, Meek D, Laiho M. Kurki S, et al. Among authors: laiho m. Cancer Cell. 2004 May;5(5):465-75. doi: 10.1016/s1535-6108(04)00110-2. Cancer Cell. 2004. PMID: 15144954 Free article.

4

Nucleophosmin, HDM2 and p53: players in UV damage incited nucleolar stress response.

Kurki S, Peltonen K, Laiho M. Kurki S, et al. Among authors: laiho m. Cell Cycle. 2004 Aug;3(8):976-9. Epub 2004 Aug 8. Cell Cycle. 2004. PMID: 15254398 Review.

5

Melanoma cell lines are susceptible to histone deacetylase inhibitor TSA provoked cell cycle arrest and apoptosis.

Peltonen K, Kiviharju TM, Järvinen PM, Ra R, Laiho M. Peltonen K, et al. Among authors: laiho m. Pigment Cell Res. 2005 Jun;18(3):196-202. doi: 10.1111/j.1600-0749.2005.00225.x. Pigment Cell Res. 2005. PMID: 15892716

6

Human prostate epithelium lacks Wee1A-mediated DNA damage-induced checkpoint enforcement.

Kiviharju-af Hällström TM, Jäämaa S, Mönkkönen M, Peltonen K, Andersson LC, Medema RH, Peehl DM, Laiho M. Kiviharju-af Hällström TM, et al. Among authors: laiho m. Proc Natl Acad Sci U S A. 2007 Apr 24;104(17):7211-6. doi: 10.1073/pnas.0609299104. Epub 2007 Apr 12. Proc Natl Acad Sci U S A. 2007. PMID: 17431037 Free PMC article.

7

Genetic changes and DNA damage responses in the prostate.

Hällström TM, Laiho M. Hällström TM, et al. Among authors: laiho m. Prostate. 2008 Jun 1;68(8):902-18. doi: 10.1002/pros.20746. Prostate. 2008. PMID: 18324675 Review.

8

Non-CDK-bound p27 (p27(NCDK)) is a marker for cell stress and is regulated through the Akt/PKB and AMPK-kinase pathways.

Björklund MA, Vaahtomeri K, Peltonen K, Viollet B, Mäkelä TP, Band AM, Laiho M. Björklund MA, et al. Among authors: laiho m. Exp Cell Res. 2010 Mar 10;316(5):762-74. doi: 10.1016/j.yexcr.2009.12.014. Epub 2009 Dec 28. Exp Cell Res. 2010. PMID: 20036235

9

Identification of novel p53 pathway activating small-molecule compounds reveals unexpected similarities with known therapeutic agents.

Peltonen K, Colis L, Liu H, Jäämaa S, Moore HM, Enbäck J, Laakkonen P, Vaahtokari A, Jones RJ, af Hällström TM, Laiho M. Peltonen K, et al. Among authors: laiho m. PLoS One. 2010 Sep 27;5(9):e12996. doi: 10.1371/journal.pone.0012996. PLoS One. 2010. PMID: 20885994 Free PMC article.

10

DNA damage recognition via activated ATM and p53 pathway in nonproliferating human prostate tissue.

Jäämaa S, Af Hällström TM, Sankila A, Rantanen V, Koistinen H, Stenman UH, Zhang Z, Yang Z, De Marzo AM, Taari K, Ruutu M, Andersson LC, Laiho M. Jäämaa S, et al. Among authors: laiho m. Cancer Res. 2010 Nov 1;70(21):8630-41. doi: 10.1158/0008-5472.CAN-10-0937. Epub 2010 Oct 26. Cancer Res. 2010. PMID: 20978201

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