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SC-39026, a serine elastase inhibitor, prevents muscularization of peripheral arteries, suggesting a mechanism of monocrotaline-induced pulmonary hypertension in rats.
Circ Res. 1989 Apr;64(4):814-25. doi: 10.1161/01.res.64.4.814.
Circ Res. 1989.
PMID: 2495195
Increased pulmonary artery elastolytic activity in adult rats with monocrotaline-induced progressive hypertensive pulmonary vascular disease compared with infant rats with nonprogressive disease.
Todorovich-Hunter L, Dodo H, Ye C, McCready L, Keeley FW, Rabinovitch M.
Todorovich-Hunter L, et al.
Am Rev Respir Dis. 1992 Jul;146(1):213-23. doi: 10.1164/ajrccm/146.1.213.
Am Rev Respir Dis. 1992.
PMID: 1626806
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Altered elastin and collagen synthesis associated with progressive pulmonary hypertension induced by monocrotaline. A biochemical and ultrastructural study.
Todorovich-Hunter L, Johnson DJ, Ranger P, Keeley FW, Rabinovitch M.
Todorovich-Hunter L, et al.
Lab Invest. 1988 Feb;58(2):184-95.
Lab Invest. 1988.
PMID: 3123799
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