Dwoskin LP - Search Results

1

2',6'-Dihalostyrylanilines, pyridines, and pyrimidines for the inhibition of the catalytic subunit of methionine S-adenosyltransferase-2.

Sviripa VM, Zhang W, Balia AG, Tsodikov OV, Nickell JR, Gizard F, Yu T, Lee EY, Dwoskin LP, Liu C, Watt DS. Sviripa VM, et al. Among authors: dwoskin lp. J Med Chem. 2014 Jul 24;57(14):6083-91. doi: 10.1021/jm5004864. Epub 2014 Jul 9. J Med Chem. 2014. PMID: 24950374 Free PMC article.

2

Subtype-selective nicotinic receptor antagonists: potential as tobacco use cessation agents.

Dwoskin LP, Sumithran SP, Zhu J, Deaciuc AG, Ayers JT, Crooks PA. Dwoskin LP, et al. Bioorg Med Chem Lett. 2004 Apr 19;14(8):1863-7. doi: 10.1016/j.bmcl.2003.10.073. Bioorg Med Chem Lett. 2004. PMID: 15050617

3

Development of subtype-selective ligands as antagonists at nicotinic receptors mediating nicotine-evoked dopamine release.

Crooks PA, Ayers JT, Xu R, Sumithran SP, Grinevich VP, Wilkins LH, Deaciuc AG, Allen DD, Dwoskin LP. Crooks PA, et al. Among authors: dwoskin lp. Bioorg Med Chem Lett. 2004 Apr 19;14(8):1869-74. doi: 10.1016/j.bmcl.2003.10.074. Bioorg Med Chem Lett. 2004. PMID: 15050618

4

Lobelane analogues as novel ligands for the vesicular monoamine transporter-2.

Zheng G, Dwoskin LP, Deaciuc AG, Zhu J, Jones MD, Crooks PA. Zheng G, et al. Among authors: dwoskin lp. Bioorg Med Chem. 2005 Jun 2;13(12):3899-909. doi: 10.1016/j.bmc.2005.04.013. Bioorg Med Chem. 2005. PMID: 15911306 Free PMC article.

5

Defunctionalized lobeline analogues: structure-activity of novel ligands for the vesicular monoamine transporter.

Zheng G, Dwoskin LP, Deaciuc AG, Norrholm SD, Crooks PA. Zheng G, et al. Among authors: dwoskin lp. J Med Chem. 2005 Aug 25;48(17):5551-60. doi: 10.1021/jm0501228. J Med Chem. 2005. PMID: 16107155 Free PMC article.

6

Synthesis and evaluation of a series of tropane analogues as novel vesicular monoamine transporter-2 ligands.

Zheng G, Dwoskin LP, Deaciuc AG, Crooks PA. Zheng G, et al. Among authors: dwoskin lp. Bioorg Med Chem Lett. 2005 Oct 15;15(20):4463-6. doi: 10.1016/j.bmcl.2005.07.032. Bioorg Med Chem Lett. 2005. PMID: 16112864 Free PMC article.

7

QSAR modeling of mono- and bis-quaternary ammonium salts that act as antagonists at neuronal nicotinic acetylcholine receptors mediating dopamine release.

Zheng F, Bayram E, Sumithran SP, Ayers JT, Zhan CG, Schmitt JD, Dwoskin LP, Crooks PA. Zheng F, et al. Among authors: dwoskin lp. Bioorg Med Chem. 2006 May 1;14(9):3017-37. doi: 10.1016/j.bmc.2005.12.036. Epub 2006 Jan 20. Bioorg Med Chem. 2006. PMID: 16431111

8

Des-keto lobeline analogs with increased potency and selectivity at dopamine and serotonin transporters.

Zheng G, Horton DB, Deaciuc AG, Dwoskin LP, Crooks PA. Zheng G, et al. Among authors: dwoskin lp. Bioorg Med Chem Lett. 2006 Oct 1;16(19):5018-21. doi: 10.1016/j.bmcl.2006.07.070. Epub 2006 Aug 14. Bioorg Med Chem Lett. 2006. PMID: 16905316 Free PMC article.

9

Modeling subtype-selective agonists binding with alpha4beta2 and alpha7 nicotinic acetylcholine receptors: effects of local binding and long-range electrostatic interactions.

Huang X, Zheng F, Chen X, Crooks PA, Dwoskin LP, Zhan CG. Huang X, et al. Among authors: dwoskin lp. J Med Chem. 2006 Dec 28;49(26):7661-74. doi: 10.1021/jm0606701. J Med Chem. 2006. PMID: 17181149

10

N, N -disubstituted piperazines and homopiperazines: synthesis and affinities at alpha4beta2* and alpha7* neuronal nicotinic acetylcholine receptors.

Chen J, Deaciuc AG, Dwoskin LP, Crooks PA, Bai D. Chen J, et al. Among authors: dwoskin lp. J Enzyme Inhib Med Chem. 2006 Dec;21(6):667-80. doi: 10.1080/14756360600900513. J Enzyme Inhib Med Chem. 2006. PMID: 17252939 Free article.

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