Shimo T - Search Results

1

Design and evaluation of locked nucleic acid-based splice-switching oligonucleotides in vitro.

Shimo T, Tachibana K, Saito K, Yoshida T, Tomita E, Waki R, Yamamoto T, Doi T, Inoue T, Kawakami J, Obika S. Shimo T, et al. Nucleic Acids Res. 2014 Jul;42(12):8174-87. doi: 10.1093/nar/gku512. Epub 2014 Jun 16. Nucleic Acids Res. 2014. PMID: 24935206 Free PMC article.

2

A novel human muscle cell model of Duchenne muscular dystrophy created by CRISPR/Cas9 and evaluation of antisense-mediated exon skipping.

Shimo T, Hosoki K, Nakatsuji Y, Yokota T, Obika S. Shimo T, et al. J Hum Genet. 2018 Mar;63(3):365-375. doi: 10.1038/s10038-017-0400-0. Epub 2018 Jan 16. J Hum Genet. 2018. PMID: 29339778

3

Construction of a tri-chromatic reporter cell line for the rapid and simple screening of splice-switching oligonucleotides targeting DMD exon 51 using high content screening.

Shimo T, Tachibana K, Obika S. Shimo T, et al. PLoS One. 2018 May 16;13(5):e0197373. doi: 10.1371/journal.pone.0197373. eCollection 2018. PLoS One. 2018. PMID: 29768479 Free PMC article.

4

Optimization of 2',4'-BNA/LNA-Based Oligonucleotides for Splicing Modulation In Vitro.

Shimo T, Obika S. Shimo T, et al. Methods Mol Biol. 2018;1828:395-411. doi: 10.1007/978-1-4939-8651-4_25. Methods Mol Biol. 2018. PMID: 30171556

5

Enhancement of exon skipping activity by reduction in the secondary structure content of LNA-based splice-switching oligonucleotides.

Shimo T , Tachibana K , Kawawaki Y , Watahiki Y , Ishigaki T , Nakatsuji Y , Hara T , Kawakami J , Obika S . Shimo T , et al. Chem Commun (Camb). 2019 Jun 11;55(48):6850-6853. doi: 10.1039/c8cc09648a. Chem Commun (Camb). 2019. PMID: 31123731

6

Design and In Vitro Evaluation of Splice-Switching Oligonucleotides Bearing Locked Nucleic Acids, Amido-Bridged Nucleic Acids, and Guanidine-Bridged Nucleic Acids.

Shimo T, Nakatsuji Y, Tachibana K, Obika S. Shimo T, et al. Int J Mol Sci. 2021 Mar 29;22(7):3526. doi: 10.3390/ijms22073526. Int J Mol Sci. 2021. PMID: 33805378 Free PMC article.

7

Design and evaluation of antisense sequence length for modified mouse U7 small nuclear RNA to induce efficient pre-messenger RNA splicing modulation in vitro.

Shimo T, Ueda O, Yamamoto S. Shimo T, et al. PLoS One. 2024 Jul 9;19(7):e0305012. doi: 10.1371/journal.pone.0305012. eCollection 2024. PLoS One. 2024. PMID: 38980892 Free PMC article.

8

Designing Effective Antisense Oligonucleotides for Exon Skipping.

Shimo T, Maruyama R, Yokota T. Shimo T, et al. Methods Mol Biol. 2018;1687:143-155. doi: 10.1007/978-1-4939-7374-3_10. Methods Mol Biol. 2018. PMID: 29067661

9

Coronal Cementum and Reduced Enamel Epithelium on Occlusal Surface of Impacted Wisdom Tooth in a Human.

Horie N, Murata M, Minamida Y, Nagayasu H, Shimo T, Akazawa T, Tsujigiwa H, Haikel Y, Nagatsuka H. Horie N, et al. Among authors: shimo t. Dent J (Basel). 2024 Oct 30;12(11):348. doi: 10.3390/dj12110348. Dent J (Basel). 2024. PMID: 39590398 Free PMC article.

10

Increased cell killing effect in neutron capture enhanced proton beam therapy.

Shiba S, Shimo T, Yamanaka M, Yagihashi T, Sakai M, Ohno T, Tokuuye K, Omura M. Shiba S, et al. Among authors: shimo t. Sci Rep. 2024 Nov 18;14(1):28484. doi: 10.1038/s41598-024-79045-3. Sci Rep. 2024. PMID: 39557960 Free PMC article.

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