Peng T - Search Results

1

Topoisomerase II inhibitors from the roots of Stellera chamaejasme L.

Liu LP, Han K, Chen W, Zhang YY, Tong LJ, Peng T, Xie H, Ding J, Wang HB. Liu LP, et al. Among authors: peng t. Bioorg Med Chem. 2014 Aug 1;22(15):4198-203. doi: 10.1016/j.bmc.2014.05.042. Epub 2014 May 29. Bioorg Med Chem. 2014. PMID: 24931277

2

Discovery and SAR of thiazolidine-2,4-dione analogues as insulin-like growth factor-1 receptor (IGF-1R) inhibitors via hierarchical virtual screening.

Liu X, Xie H, Luo C, Tong L, Wang Y, Peng T, Ding J, Jiang H, Li H. Liu X, et al. Among authors: peng t. J Med Chem. 2010 Mar 25;53(6):2661-5. doi: 10.1021/jm901798e. J Med Chem. 2010. PMID: 20178321 Free article.

3

Naphthalimides exhibit in vitro antiproliferative and antiangiogenic activities by inhibiting both topoisomerase II (topo II) and receptor tyrosine kinases (RTKs).

Wang X, Chen Z, Tong L, Tan S, Zhou W, Peng T, Han K, Ding J, Xie H, Xu Y. Wang X, et al. Among authors: peng t. Eur J Med Chem. 2013 Jul;65:477-86. doi: 10.1016/j.ejmech.2013.05.002. Epub 2013 May 14. Eur J Med Chem. 2013. PMID: 23770449

4

Design, synthesis and biological evaluation of novel 4-anilinoquinazolines with C-6 urea-linked side chains as inhibitors of the epidermal growth factor receptor.

Zhang X, Peng T, Ji X, Li J, Tong L, Li Z, Yang W, Xu Y, Li M, Ding J, Jiang H, Xie H, Liu H. Zhang X, et al. Among authors: peng t. Bioorg Med Chem. 2013 Dec 15;21(24):7988-98. doi: 10.1016/j.bmc.2013.09.049. Epub 2013 Oct 2. Bioorg Med Chem. 2013. PMID: 24183742

5

Design, synthesis and biological evaluation of novel 6-alkenylamides substituted of 4-anilinothieno[2,3-d]pyrimidines as irreversible epidermal growth factor receptor inhibitors.

Ji X, Peng T, Zhang X, Li J, Yang W, Tong L, Qu R, Jiang H, Ding J, Xie H, Liu H. Ji X, et al. Among authors: peng t. Bioorg Med Chem. 2014 Apr 1;22(7):2366-78. doi: 10.1016/j.bmc.2014.01.035. Epub 2014 Jan 31. Bioorg Med Chem. 2014. PMID: 24565969

6

Establishment of platform for screening insulin-like growth factor-1 receptor inhibitors and evaluation of novel inhibitors.

Tong LJ, Xie H, Peng T, Liu XF, Xin XL, Huang X, Chen SM, Liu HY, Li HL, Geng MY, Yin M, Ding J. Tong LJ, et al. Among authors: peng t. Acta Pharmacol Sin. 2011 Jul;32(7):930-8. doi: 10.1038/aps.2011.23. Epub 2011 Jun 6. Acta Pharmacol Sin. 2011. PMID: 21643004 Free PMC article.

7

Discovery of a New Series of Naphthamides as Potent VEGFR-2 Kinase Inhibitors.

Lv Y, Li M, Liu T, Tong L, Peng T, Wei L, Ding J, Xie H, Duan W. Lv Y, et al. Among authors: peng t. ACS Med Chem Lett. 2014 Feb 24;5(5):592-7. doi: 10.1021/ml5000417. eCollection 2014 May 8. ACS Med Chem Lett. 2014. PMID: 24900886 Free PMC article.

8

DW10075, a novel selective and small-molecule inhibitor of VEGFR, exhibits antitumor activities both in vitro and in vivo.

Li MY, Lv YC, Tong LJ, Peng T, Qu R, Zhang T, Sun YM, Chen Y, Wei LX, Geng MY, Duan WH, Xie H, Ding J. Li MY, et al. Among authors: peng t. Acta Pharmacol Sin. 2016 Mar;37(3):398-407. doi: 10.1038/aps.2015.117. Epub 2016 Jan 25. Acta Pharmacol Sin. 2016. PMID: 26806300 Free PMC article.

9

Discovery of N-(3-bromo-1H-indol-5-yl)-quinazolin-4-amine as an effective molecular skeleton to develop reversible/irreversible pan-HER inhibitors.

Tang Q, Peng T, Hu J, Zhang T, Chen P, Chen D, Wang Y, Chen L, Tong L, Chen Y, Xie H, Liang G. Tang Q, et al. Among authors: peng t. Eur J Med Chem. 2022 Apr 5;233:114249. doi: 10.1016/j.ejmech.2022.114249. Epub 2022 Mar 2. Eur J Med Chem. 2022. PMID: 35259690

10

Identification of DW532 as a novel anti-tumor agent targeting both kinases and tubulin.

Peng T, Wu JR, Tong LJ, Li MY, Chen F, Leng YX, Qu R, Han K, Su Y, Chen Y, Duan WH, Xie H, Ding J. Peng T, et al. Acta Pharmacol Sin. 2014 Jul;35(7):916-28. doi: 10.1038/aps.2014.33. Epub 2014 May 26. Acta Pharmacol Sin. 2014. PMID: 24858311 Free PMC article.

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