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Intracerebral accumulation of glutaric and 3-hydroxyglutaric acids secondary to limited flux across the blood-brain barrier constitute a biochemical risk factor for neurodegeneration in glutaryl-CoA dehydrogenase deficiency.
Sauer SW, Okun JG, Fricker G, Mahringer A, Müller I, Crnic LR, Mühlhausen C, Hoffmann GF, Hörster F, Goodman SI, Harding CO, Koeller DM, Kölker S. Sauer SW, et al. Among authors: mahringer a. J Neurochem. 2006 May;97(3):899-910. doi: 10.1111/j.1471-4159.2006.03813.x. Epub 2006 Mar 29. J Neurochem. 2006. PMID: 16573641 Free article.
Glutaric aciduria type I and methylmalonic aciduria: simulation of cerebral import and export of accumulating neurotoxic dicarboxylic acids in in vitro models of the blood-brain barrier and the choroid plexus.
Sauer SW, Opp S, Mahringer A, Kamiński MM, Thiel C, Okun JG, Fricker G, Morath MA, Kölker S. Sauer SW, et al. Among authors: mahringer a. Biochim Biophys Acta. 2010 Jun;1802(6):552-60. doi: 10.1016/j.bbadis.2010.03.003. Epub 2010 Mar 17. Biochim Biophys Acta. 2010. PMID: 20302929 Free article.
Design of novel artemisinin-like derivatives with cytotoxic and anti-angiogenic properties.
Soomro S, Langenberg T, Mahringer A, Konkimalla VB, Horwedel C, Holenya P, Brand A, Cetin C, Fricker G, Dewerchin M, Carmeliet P, Conway EM, Jansen H, Efferth T. Soomro S, et al. Among authors: mahringer a. J Cell Mol Med. 2011 May;15(5):1122-35. doi: 10.1111/j.1582-4934.2010.01120.x. Epub 2010 Jul 12. J Cell Mol Med. 2011. PMID: 20629994 Free PMC article.
39 results