Guicherit O - Search Results

1

Chemogenetic evaluation of the mitotic kinesin CENP-E reveals a critical role in triple-negative breast cancer.

Kung PP, Martinez R, Zhu Z, Zager M, Blasina A, Rymer I, Hallin J, Xu M, Carroll C, Chionis J, Wells P, Kozminski K, Fan J, Guicherit O, Huang B, Cui M, Liu C, Huang Z, Sistla A, Yang J, Murray BW. Kung PP, et al. Among authors: guicherit o. Mol Cancer Ther. 2014 Aug;13(8):2104-15. doi: 10.1158/1535-7163.MCT-14-0083-T. Epub 2014 Jun 13. Mol Cancer Ther. 2014. PMID: 24928852

2

Resistance to dual blockade of the kinases PI3K and mTOR in KRAS-mutant colorectal cancer models results in combined sensitivity to inhibition of the receptor tyrosine kinase EGFR.

Belmont PJ, Jiang P, McKee TD, Xie T, Isaacson J, Baryla NE, Roper J, Sinnamon MJ, Lee NV, Kan JL, Guicherit O, Wouters BG, O'Brien CA, Shields D, Olson P, VanArsdale T, Weinrich SL, Rejto P, Christensen JG, Fantin VR, Hung KE, Martin ES. Belmont PJ, et al. Among authors: o brien ca, guicherit o. Sci Signal. 2014 Nov 11;7(351):ra107. doi: 10.1126/scisignal.2005516. Sci Signal. 2014. PMID: 25389372

3

Identification of a small molecule inhibitor of the hedgehog signaling pathway: effects on basal cell carcinoma-like lesions.

Williams JA, Guicherit OM, Zaharian BI, Xu Y, Chai L, Wichterle H, Kon C, Gatchalian C, Porter JA, Rubin LL, Wang FY. Williams JA, et al. Proc Natl Acad Sci U S A. 2003 Apr 15;100(8):4616-21. doi: 10.1073/pnas.0732813100. Epub 2003 Apr 4. Proc Natl Acad Sci U S A. 2003. PMID: 12679522 Free PMC article.

4

IFNalpha induces Fas expression and apoptosis in hedgehog pathway activated BCC cells through inhibiting Ras-Erk signaling.

Li C, Chi S, He N, Zhang X, Guicherit O, Wagner R, Tyring S, Xie J. Li C, et al. Among authors: guicherit o. Oncogene. 2004 Feb 26;23(8):1608-17. doi: 10.1038/sj.onc.1207273. Oncogene. 2004. PMID: 14647422

5

Potent inhibitors of the hedgehog signaling pathway.

Brunton SA, Stibbard JH, Rubin LL, Kruse LI, Guicherit OM, Boyd EA, Price S. Brunton SA, et al. J Med Chem. 2008 Mar 13;51(5):1108-10. doi: 10.1021/jm070694n. Epub 2008 Feb 15. J Med Chem. 2008. PMID: 18275133

6

Potent agonists of the Hedgehog signaling pathway.

Brunton SA, Stibbard JH, Rubin LL, Guicherit OM, Kruse LI, Price S, di Lucrezia R, MacKinnon CH, Avery A, Park Y, Buxton D, Boyd EA. Brunton SA, et al. Bioorg Med Chem Lett. 2009 Aug 1;19(15):4308-11. doi: 10.1016/j.bmcl.2009.05.096. Epub 2009 May 29. Bioorg Med Chem Lett. 2009. PMID: 19500978

7

Small-molecule modulators of Hedgehog signaling: identification and characterization of Smoothened agonists and antagonists.

Frank-Kamenetsky M, Zhang XM, Bottega S, Guicherit O, Wichterle H, Dudek H, Bumcrot D, Wang FY, Jones S, Shulok J, Rubin LL, Porter JA. Frank-Kamenetsky M, et al. Among authors: guicherit o. J Biol. 2002 Nov 6;1(2):10. doi: 10.1186/1475-4924-1-10. J Biol. 2002. PMID: 12437772 Free PMC article.

8

Ex vivo fluorescence-guided resection margin assessment in breast cancer surgery using a topically applied, cathepsin-activatable imaging agent.

Linders DGJ, Bijlstra OD, Walker E, March TL, Pool M, Valentijn ARPM, Dijkhuis TH, Woltering JN, Pijl FR, Noordam G, van den Burg D, van der Sijp JRM, Guicherit OR, Marinelli AWKS, Burggraaf J, Rissmann R, Bogyo M, Hilling DE, Kuppen PJK, Straight B, Straver ME, Hazelbag HM, Basilion JP, Vahrmeijer AL. Linders DGJ, et al. Among authors: guicherit or. Pharmacol Res. 2024 Nov;209:107464. doi: 10.1016/j.phrs.2024.107464. Epub 2024 Oct 12. Pharmacol Res. 2024. PMID: 39401538 Free article.

9

Perceptions and beliefs of general practitioners on their role in the cancer screening programmes in the Netherlands: a mixed-methods study.

Bongaerts THG, Büchner FL, Nierkens V, Crone MR, Guicherit OR, Numans ME. Bongaerts THG, et al. Among authors: guicherit or. BMC Prim Care. 2024 Apr 24;25(1):129. doi: 10.1186/s12875-024-02394-5. BMC Prim Care. 2024. PMID: 38658815 Free PMC article.

10

Attendance characteristics of the breast and colorectal cancer screening programmes in a highly urbanised region of the Netherlands: a retrospective observational study.

Bongaerts THG, Büchner FL, de Munck L, Elferink MAG, Guicherit OR, Numans ME. Bongaerts THG, et al. Among authors: guicherit or. BMJ Open. 2023 Jun 23;13(6):e071354. doi: 10.1136/bmjopen-2022-071354. BMJ Open. 2023. PMID: 37355264 Free PMC article.

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