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Page 1
Metabolic dysfunction consistent with premature aging results from deletion of Pim kinases.
Din S, Konstandin MH, Johnson B, Emathinger J, Völkers M, Toko H, Collins B, Ormachea L, Samse K, Kubli DA, De La Torre A, Kraft AS, Gustafsson AB, Kelly DP, Sussman MA. Din S, et al. Among authors: sussman ma. Circ Res. 2014 Jul 18;115(3):376-87. doi: 10.1161/CIRCRESAHA.115.304441. Epub 2014 Jun 10. Circ Res. 2014. PMID: 24916111 Free PMC article.
Pim-1 regulates cardiomyocyte survival downstream of Akt.
Muraski JA, Rota M, Misao Y, Fransioli J, Cottage C, Gude N, Esposito G, Delucchi F, Arcarese M, Alvarez R, Siddiqi S, Emmanuel GN, Wu W, Fischer K, Martindale JJ, Glembotski CC, Leri A, Kajstura J, Magnuson N, Berns A, Beretta RM, Houser SR, Schaefer EM, Anversa P, Sussman MA. Muraski JA, et al. Among authors: sussman ma. Nat Med. 2007 Dec;13(12):1467-75. doi: 10.1038/nm1671. Epub 2007 Nov 25. Nat Med. 2007. PMID: 18037896
Activation of Notch-mediated protective signaling in the myocardium.
Gude NA, Emmanuel G, Wu W, Cottage CT, Fischer K, Quijada P, Muraski JA, Alvarez R, Rubio M, Schaefer E, Sussman MA. Gude NA, et al. Among authors: sussman ma. Circ Res. 2008 May 9;102(9):1025-35. doi: 10.1161/CIRCRESAHA.107.164749. Epub 2008 Mar 27. Circ Res. 2008. PMID: 18369158 Free PMC article.
Pim-1 kinase antagonizes aspects of myocardial hypertrophy and compensation to pathological pressure overload.
Muraski JA, Fischer KM, Wu W, Cottage CT, Quijada P, Mason M, Din S, Gude N, Alvarez R Jr, Rota M, Kajstura J, Wang Z, Schaefer E, Chen X, MacDonnel S, Magnuson N, Houser SR, Anversa P, Sussman MA. Muraski JA, et al. Among authors: sussman ma. Proc Natl Acad Sci U S A. 2008 Sep 16;105(37):13889-94. doi: 10.1073/pnas.0709135105. Epub 2008 Sep 10. Proc Natl Acad Sci U S A. 2008. PMID: 18784362 Free PMC article.
224 results