Song ES - Search Results

1

Obesity and diabetes cause cognitive dysfunction in the absence of accelerated β-amyloid deposition in a novel murine model of mixed or vascular dementia.

Niedowicz DM, Reeves VL, Platt TL, Kohler K, Beckett TL, Powell DK, Lee TL, Sexton TR, Song ES, Brewer LD, Latimer CS, Kraner SD, Larson KL, Ozcan S, Norris CM, Hersh LB, Porter NM, Wilcock DM, Murphy MP. Niedowicz DM, et al. Among authors: song es. Acta Neuropathol Commun. 2014 Jun 10;2:64. doi: 10.1186/2051-5960-2-64. Acta Neuropathol Commun. 2014. PMID: 24916066 Free PMC article.

2

Analysis of the subsite specificity of rat insulysin using fluorogenic peptide substrates.

Song ES, Mukherjee A, Juliano MA, Pyrek JS, Goodman JP Jr, Juliano L, Hersh LB. Song ES, et al. J Biol Chem. 2001 Jan 12;276(2):1152-5. doi: 10.1074/jbc.M008702200. J Biol Chem. 2001. PMID: 11042190 Free article.

3

Insulysin hydrolyzes amyloid beta peptides to products that are neither neurotoxic nor deposit on amyloid plaques.

Mukherjee A, Song E, Kihiko-Ehmann M, Goodman JP Jr, Pyrek JS, Estus S, Hersh LB. Mukherjee A, et al. J Neurosci. 2000 Dec 1;20(23):8745-9. doi: 10.1523/JNEUROSCI.20-23-08745.2000. J Neurosci. 2000. PMID: 11102481 Free PMC article.

4

Substrate activation of insulin-degrading enzyme (insulysin). A potential target for drug development.

Song ES, Juliano MA, Juliano L, Hersh LB. Song ES, et al. J Biol Chem. 2003 Dec 12;278(50):49789-94. doi: 10.1074/jbc.M308983200. Epub 2003 Oct 2. J Biol Chem. 2003. PMID: 14527953 Free article.

5

ATP effects on insulin-degrading enzyme are mediated primarily through its triphosphate moiety.

Song ES, Juliano MA, Juliano L, Fried MG, Wagner SL, Hersh LB. Song ES, et al. J Biol Chem. 2004 Dec 24;279(52):54216-20. doi: 10.1074/jbc.M411177200. Epub 2004 Oct 19. J Biol Chem. 2004. PMID: 15494400 Free article.

6

Mutation of active site residues of insulin-degrading enzyme alters allosteric interactions.

Song ES, Daily A, Fried MG, Juliano MA, Juliano L, Hersh LB. Song ES, et al. J Biol Chem. 2005 May 6;280(18):17701-6. doi: 10.1074/jbc.M501896200. Epub 2005 Mar 3. J Biol Chem. 2005. PMID: 15749695 Free article.

7

Insulysin: an allosteric enzyme as a target for Alzheimer's disease.

Song ES, Hersh LB. Song ES, et al. J Mol Neurosci. 2005;25(3):201-6. doi: 10.1385/JMN:25:3:201. J Mol Neurosci. 2005. PMID: 15800373

8

Susceptibility of amyloid beta peptide degrading enzymes to oxidative damage: a potential Alzheimer's disease spiral.

Shinall H, Song ES, Hersh LB. Shinall H, et al. Among authors: song es. Biochemistry. 2005 Nov 22;44(46):15345-50. doi: 10.1021/bi050650l. Biochemistry. 2005. PMID: 16285738

9

Proteolytic fragments of insulysin (IDE) retain substrate binding but lose allosteric regulation.

Song ES, Cady C, Fried MG, Hersh LB. Song ES, et al. Biochemistry. 2006 Dec 19;45(50):15085-91. doi: 10.1021/bi061298u. Biochemistry. 2006. PMID: 17154546 Free PMC article.

10

In vitro and in vivo degradation of Abeta peptide by peptidases coupled to erythrocytes.

Liu Y, Guan H, Beckett TL, Juliano MA, Juliano L, Song ES, Chow KM, Murphy MP, Hersh LB. Liu Y, et al. Among authors: song es. Peptides. 2007 Dec;28(12):2348-55. doi: 10.1016/j.peptides.2007.09.015. Epub 2007 Sep 29. Peptides. 2007. PMID: 17988763 Free PMC article.

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