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A hormone-dependent feedback-loop controls androgen receptor levels by limiting MID1, a novel translation enhancer and promoter of oncogenic signaling.
Köhler A, Demir U, Kickstein E, Krauss S, Aigner J, Aranda-Orgillés B, Karagiannidis AI, Achmüller C, Bu H, Wunderlich A, Schweiger MR, Schaefer G, Schweiger S, Klocker H, Schneider R. Köhler A, et al. Among authors: krauss s. Mol Cancer. 2014 Jun 9;13:146. doi: 10.1186/1476-4598-13-146. Mol Cancer. 2014. PMID: 24913494 Free PMC article.
The E3 ubiquitin ligase MID1 catalyzes ubiquitination and cleavage of Fu.
Schweiger S, Dorn S, Fuchs M, Köhler A, Matthes F, Müller EC, Wanker E, Schneider R, Krauß S. Schweiger S, et al. Among authors: krauss s. J Biol Chem. 2014 Nov 14;289(46):31805-31817. doi: 10.1074/jbc.M113.541219. Epub 2014 Oct 2. J Biol Chem. 2014. PMID: 25278022 Free PMC article.
Biguanide metformin acts on tau phosphorylation via mTOR/protein phosphatase 2A (PP2A) signaling.
Kickstein E, Krauss S, Thornhill P, Rutschow D, Zeller R, Sharkey J, Williamson R, Fuchs M, Köhler A, Glossmann H, Schneider R, Sutherland C, Schweiger S. Kickstein E, et al. Among authors: krauss s. Proc Natl Acad Sci U S A. 2010 Dec 14;107(50):21830-5. doi: 10.1073/pnas.0912793107. Epub 2010 Nov 22. Proc Natl Acad Sci U S A. 2010. PMID: 21098287 Free PMC article.
Control of mTORC1 signaling by the Opitz syndrome protein MID1.
Liu E, Knutzen CA, Krauss S, Schweiger S, Chiang GG. Liu E, et al. Among authors: krauss s. Proc Natl Acad Sci U S A. 2011 May 24;108(21):8680-5. doi: 10.1073/pnas.1100131108. Epub 2011 May 9. Proc Natl Acad Sci U S A. 2011. PMID: 21555591 Free PMC article.
718 results