Rudolph MJ - Search Results

1

Crystal structures of ricin toxin's enzymatic subunit (RTA) in complex with neutralizing and non-neutralizing single-chain antibodies.

Rudolph MJ, Vance DJ, Cheung J, Franklin MC, Burshteyn F, Cassidy MS, Gary EN, Herrera C, Shoemaker CB, Mantis NJ. Rudolph MJ, et al. J Mol Biol. 2014 Aug 26;426(17):3057-68. doi: 10.1016/j.jmb.2014.05.026. Epub 2014 Jun 4. J Mol Biol. 2014. PMID: 24907552 Free PMC article.

2

Structural analysis of nested neutralizing and non-neutralizing B cell epitopes on ricin toxin's enzymatic subunit.

Rudolph MJ, Vance DJ, Cassidy MS, Rong Y, Shoemaker CB, Mantis NJ. Rudolph MJ, et al. Proteins. 2016 Aug;84(8):1162-72. doi: 10.1002/prot.25062. Epub 2016 Jun 15. Proteins. 2016. PMID: 27159829 Free PMC article.

3

Structural Analysis of Single Domain Antibodies Bound to a Second Neutralizing Hot Spot on Ricin Toxin's Enzymatic Subunit.

Rudolph MJ, Vance DJ, Cassidy MS, Rong Y, Mantis NJ. Rudolph MJ, et al. J Biol Chem. 2017 Jan 20;292(3):872-883. doi: 10.1074/jbc.M116.758102. Epub 2016 Nov 30. J Biol Chem. 2017. PMID: 27903650 Free PMC article.

4

Using homology modeling to interrogate binding affinity in neutralization of ricin toxin by a family of single domain antibodies.

Bazzoli A, Vance DJ, Rudolph MJ, Rong Y, Angalakurthi SK, Toth RT 4th, Middaugh CR, Volkin DB, Weis DD, Karanicolas J, Mantis NJ. Bazzoli A, et al. Among authors: rudolph mj. Proteins. 2017 Nov;85(11):1994-2008. doi: 10.1002/prot.25353. Epub 2017 Aug 4. Proteins. 2017. PMID: 28718923 Free PMC article.

5

Contribution of an unusual CDR2 element of a single domain antibody in ricin toxin binding affinity and neutralizing activity.

Rudolph MJ, Vance DJ, Kelow S, Angalakurthi SK, Nguyen S, Davis SA, Rong Y, Middaugh CR, Weis DD, Dunbrack R Jr, Karanicolas J, Mantis NJ. Rudolph MJ, et al. Protein Eng Des Sel. 2018 Jul 1;31(7-8):277-287. doi: 10.1093/protein/gzy022. Protein Eng Des Sel. 2018. PMID: 30265352 Free PMC article.

6

Intracellular Neutralization of Ricin Toxin by Single-domain Antibodies Targeting the Active Site.

Rudolph MJ, Czajka TF, Davis SA, Thi Nguyen CM, Li XP, Tumer NE, Vance DJ, Mantis NJ. Rudolph MJ, et al. J Mol Biol. 2020 Feb 14;432(4):1109-1125. doi: 10.1016/j.jmb.2020.01.006. Epub 2020 Jan 10. J Mol Biol. 2020. PMID: 31931008 Free PMC article.

7

Structural Analysis of Toxin-Neutralizing, Single-Domain Antibodies that Bridge Ricin's A-B Subunit Interface.

Rudolph MJ, Poon AY, Kavaliauskiene S, Myrann AG, Reynolds-Peterson C, Davis SA, Sandvig K, Vance DJ, Mantis NJ. Rudolph MJ, et al. J Mol Biol. 2021 Jul 23;433(15):167086. doi: 10.1016/j.jmb.2021.167086. Epub 2021 Jun 3. J Mol Biol. 2021. PMID: 34089718

8

Single-domain antibodies neutralize ricin toxin intracellularly by blocking access to ribosomal P-stalk proteins.

Czajka TF, Vance DJ, Davis S, Rudolph MJ, Mantis NJ. Czajka TF, et al. Among authors: rudolph mj. J Biol Chem. 2022 Apr;298(4):101742. doi: 10.1016/j.jbc.2022.101742. Epub 2022 Feb 17. J Biol Chem. 2022. PMID: 35182523 Free PMC article.

9

Structures of human acetylcholinesterase in complex with pharmacologically important ligands.

Cheung J, Rudolph MJ, Burshteyn F, Cassidy MS, Gary EN, Love J, Franklin MC, Height JJ. Cheung J, et al. Among authors: rudolph mj. J Med Chem. 2012 Nov 26;55(22):10282-6. doi: 10.1021/jm300871x. Epub 2012 Nov 12. J Med Chem. 2012. PMID: 23035744

10

Structures of paraoxon-inhibited human acetylcholinesterase reveal perturbations of the acyl loop and the dimer interface.

Franklin MC, Rudolph MJ, Ginter C, Cassidy MS, Cheung J. Franklin MC, et al. Among authors: rudolph mj. Proteins. 2016 Sep;84(9):1246-56. doi: 10.1002/prot.25073. Epub 2016 Jun 3. Proteins. 2016. PMID: 27191504

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