Klein WL - Search Results

1

Intracellular Aβ pathology and early cognitive impairments in a transgenic rat overexpressing human amyloid precursor protein: a multidimensional study.

Iulita MF, Allard S, Richter L, Munter LM, Ducatenzeiler A, Weise C, Do Carmo S, Klein WL, Multhaup G, Cuello AC. Iulita MF, et al. Among authors: klein wl. Acta Neuropathol Commun. 2014 Jun 5;2:61. doi: 10.1186/2051-5960-2-61. Acta Neuropathol Commun. 2014. PMID: 24903713 Free PMC article.

2

Intracellular Aβ-oligomers and early inflammation in a model of Alzheimer's disease.

Ferretti MT, Bruno MA, Ducatenzeiler A, Klein WL, Cuello AC. Ferretti MT, et al. Among authors: klein wl. Neurobiol Aging. 2012 Jul;33(7):1329-42. doi: 10.1016/j.neurobiolaging.2011.01.007. Epub 2011 Mar 16. Neurobiol Aging. 2012. PMID: 21414686

3

Early intraneuronal amyloid triggers neuron-derived inflammatory signaling in APP transgenic rats and human brain.

Welikovitch LA, Do Carmo S, Maglóczky Z, Malcolm JC, Lőke J, Klein WL, Freund T, Cuello AC. Welikovitch LA, et al. Among authors: klein wl. Proc Natl Acad Sci U S A. 2020 Mar 24;117(12):6844-6854. doi: 10.1073/pnas.1914593117. Epub 2020 Mar 6. Proc Natl Acad Sci U S A. 2020. PMID: 32144141 Free PMC article.

4

Amyloid β oligomers in Alzheimer's disease pathogenesis, treatment, and diagnosis.

Viola KL, Klein WL. Viola KL, et al. Among authors: klein wl. Acta Neuropathol. 2015 Feb;129(2):183-206. doi: 10.1007/s00401-015-1386-3. Epub 2015 Jan 22. Acta Neuropathol. 2015. PMID: 25604547 Free PMC article. Review.

5

Intraneuronal aggregation of the β-CTF fragment of APP (C99) induces Aβ-independent lysosomal-autophagic pathology.

Lauritzen I, Pardossi-Piquard R, Bourgeois A, Pagnotta S, Biferi MG, Barkats M, Lacor P, Klein W, Bauer C, Checler F. Lauritzen I, et al. Acta Neuropathol. 2016 Aug;132(2):257-276. doi: 10.1007/s00401-016-1577-6. Epub 2016 Apr 30. Acta Neuropathol. 2016. PMID: 27138984 Free PMC article.

6

Deficiency of TYROBP, an adapter protein for TREM2 and CR3 receptors, is neuroprotective in a mouse model of early Alzheimer's pathology.

Haure-Mirande JV, Audrain M, Fanutza T, Kim SH, Klein WL, Glabe C, Readhead B, Dudley JT, Blitzer RD, Wang M, Zhang B, Schadt EE, Gandy S, Ehrlich ME. Haure-Mirande JV, et al. Among authors: klein wl. Acta Neuropathol. 2017 Nov;134(5):769-788. doi: 10.1007/s00401-017-1737-3. Epub 2017 Jun 13. Acta Neuropathol. 2017. PMID: 28612290 Free PMC article.

7

Novel demonstration of amyloid-β oligomers in sporadic inclusion-body myositis muscle fibers.

Nogalska A, D'Agostino C, Engel WK, Klein WL, Askanas V. Nogalska A, et al. Among authors: klein wl. Acta Neuropathol. 2010 Nov;120(5):661-6. doi: 10.1007/s00401-010-0737-3. Epub 2010 Aug 15. Acta Neuropathol. 2010. PMID: 20711838

8

Unexpected partial correction of metabolic and behavioral phenotypes of Alzheimer's APP/PSEN1 mice by gene targeting of diabetes/Alzheimer's-related Sorcs1.

Knight EM, Ruiz HH, Kim SH, Harte JC, Hsieh W, Glabe C, Klein WL, Attie AD, Buettner C, Ehrlich ME, Gandy S. Knight EM, et al. Among authors: klein wl. Acta Neuropathol Commun. 2016 Feb 25;4:16. doi: 10.1186/s40478-016-0282-y. Acta Neuropathol Commun. 2016. PMID: 26916443 Free PMC article.

9

Alzheimer's disease-like pathology induced by amyloid-β oligomers in nonhuman primates.

Forny-Germano L, Lyra e Silva NM, Batista AF, Brito-Moreira J, Gralle M, Boehnke SE, Coe BC, Lablans A, Marques SA, Martinez AM, Klein WL, Houzel JC, Ferreira ST, Munoz DP, De Felice FG. Forny-Germano L, et al. Among authors: klein wl. J Neurosci. 2014 Oct 8;34(41):13629-43. doi: 10.1523/JNEUROSCI.1353-14.2014. J Neurosci. 2014. PMID: 25297091 Free PMC article.

10

Females exhibit more extensive amyloid, but not tau, pathology in an Alzheimer transgenic model.

Hirata-Fukae C, Li HF, Hoe HS, Gray AJ, Minami SS, Hamada K, Niikura T, Hua F, Tsukagoshi-Nagai H, Horikoshi-Sakuraba Y, Mughal M, Rebeck GW, LaFerla FM, Mattson MP, Iwata N, Saido TC, Klein WL, Duff KE, Aisen PS, Matsuoka Y. Hirata-Fukae C, et al. Among authors: klein wl. Brain Res. 2008 Jun 24;1216:92-103. doi: 10.1016/j.brainres.2008.03.079. Epub 2008 Apr 10. Brain Res. 2008. PMID: 18486110

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