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Calcium channel antagonists discovered by a multidisciplinary approach.
Carosati E, Cruciani G, Chiarini A, Budriesi R, Ioan P, Spisani R, Spinelli D, Cosimelli B, Fusi F, Frosini M, Matucci R, Gasparrini F, Ciogli A, Stephens PJ, Devlin FJ. Carosati E, et al. Among authors: cosimelli b. J Med Chem. 2006 Aug 24;49(17):5206-16. doi: 10.1021/jm0604373. J Med Chem. 2006. PMID: 16913709
Playing with opening and closing of heterocycles: using the cusmano-ruccia reaction to develop a novel class of oxadiazolothiazinones, active as calcium channel modulators and P-glycoprotein inhibitors.
Spinelli D, Budriesi R, Cosimelli B, Severi E, Micucci M, Baroni M, Fusi F, Ioan P, Cross S, Frosini M, Saponara S, Matucci R, Rosano C, Viale M, Chiarini A, Carosati E. Spinelli D, et al. Among authors: cosimelli b. Molecules. 2014 Oct 14;19(10):16543-72. doi: 10.3390/molecules191016543. Molecules. 2014. PMID: 25317581 Free PMC article.
49 results