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Page 1
Optimization of a Potent, Orally Active S1P1 Agonist Containing a Quinolinone Core.
Harrington PE, Croghan MD, Fotsch C, Frohn M, Lanman BA, Pennington LD, Pickrell AJ, Reed AB, Sham KK, Tasker A, Arnett HA, Fiorino M, Lee MR, McElvain M, Morrison HG, Xu H, Xu Y, Zhang X, Wong M, Cee VJ. Harrington PE, et al. Among authors: morrison hg. ACS Med Chem Lett. 2011 Nov 23;3(1):74-8. doi: 10.1021/ml200252b. eCollection 2012 Jan 12. ACS Med Chem Lett. 2011. PMID: 24900374 Free PMC article.
Quinolinone-based agonists of S1P₁: use of a N-scan SAR strategy to optimize in vitro and in vivo activity.
Pennington LD, Croghan MD, Sham KK, Pickrell AJ, Harrington PE, Frohn MJ, Lanman BA, Reed AB, Lee MR, Xu H, McElvain M, Xu Y, Zhang X, Fiorino M, Horner M, Morrison HG, Arnett HA, Fotsch C, Tasker AS, Wong M, Cee VJ. Pennington LD, et al. Among authors: morrison hg. Bioorg Med Chem Lett. 2012 Jan 1;22(1):527-31. doi: 10.1016/j.bmcl.2011.10.085. Epub 2011 Nov 4. Bioorg Med Chem Lett. 2012. PMID: 22104144
4-Methoxy-N-[2-(trifluoromethyl)biphenyl-4-ylcarbamoyl]nicotinamide: A Potent and Selective Agonist of S1P1.
Pennington LD, Sham KK, Pickrell AJ, Harrington PE, Frohn MJ, Lanman BA, Reed AB, Croghan MD, Lee MR, Xu H, McElvain M, Xu Y, Zhang X, Fiorino M, Horner M, Morrison HG, Arnett HA, Fotsch C, Wong M, Cee VJ. Pennington LD, et al. Among authors: morrison hg. ACS Med Chem Lett. 2011 Jul 29;2(10):752-7. doi: 10.1021/ml2001399. eCollection 2011 Oct 13. ACS Med Chem Lett. 2011. PMID: 24900263 Free PMC article.
A global comparison of surface and subsurface microbiomes reveals large-scale biodiversity gradients, and a marine-terrestrial divide.
Ruff SE, de Angelis IH, Mullis M, Payet JP, Magnabosco C, Lloyd KG, Sheik CS, Steen AD, Shipunova A, Morozov A, Reese BK, Bradley JA, Lemonnier C, Schrenk MO, Joye SB, Huber JA, Probst AJ, Morrison HG, Sogin ML, Ladau J, Colwell F. Ruff SE, et al. Among authors: morrison hg. Sci Adv. 2024 Dec 20;10(51):eadq0645. doi: 10.1126/sciadv.adq0645. Epub 2024 Dec 18. Sci Adv. 2024. PMID: 39693444 Free PMC article.
A novel conjugative transposon carrying an autonomously amplified plasmid.
Vineis JH, Reznikoff WS, Antonopoulos DA, Koval J, Chang E, Fallon BR, Paul BG, Morrison HG, Sogin ML. Vineis JH, et al. Among authors: morrison hg. mBio. 2024 Feb 14;15(2):e0278723. doi: 10.1128/mbio.02787-23. Epub 2024 Jan 23. mBio. 2024. PMID: 38259081 Free PMC article.
132 results