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The Discovery of VX-745: A Novel and Selective p38α Kinase Inhibitor.
Duffy JP, Harrington EM, Salituro FG, Cochran JE, Green J, Gao H, Bemis GW, Evindar G, Galullo VP, Ford PJ, Germann UA, Wilson KP, Bellon SF, Chen G, Taslimi P, Jones P, Huang C, Pazhanisamy S, Wang YM, Murcko MA, Su MS. Duffy JP, et al. Among authors: wilson kp. ACS Med Chem Lett. 2011 Jul 28;2(10):758-63. doi: 10.1021/ml2001455. eCollection 2011 Oct 13. ACS Med Chem Lett. 2011. PMID: 24900264 Free PMC article.
Inhibitors of hepatitis C virus NS3.4A protease. Part 3: P2 proline variants.
Perni RB, Farmer LJ, Cottrell KM, Court JJ, Courtney LF, Deininger DD, Gates CA, Harbeson SL, Kim JL, Lin C, Lin K, Luong YP, Maxwell JP, Murcko MA, Pitlik J, Rao BG, Schairer WC, Tung RD, Van Drie JH, Wilson K, Thomson JA. Perni RB, et al. Bioorg Med Chem Lett. 2004 Apr 19;14(8):1939-42. doi: 10.1016/j.bmcl.2004.01.078. Bioorg Med Chem Lett. 2004. PMID: 15050632
Chemogenomic approaches to drug discovery.
Caron PR, Mullican MD, Mashal RD, Wilson KP, Su MS, Murcko MA. Caron PR, et al. Among authors: wilson kp. Curr Opin Chem Biol. 2001 Aug;5(4):464-70. doi: 10.1016/s1367-5931(00)00229-5. Curr Opin Chem Biol. 2001. PMID: 11470611 Review. No abstract available.
Crystal structure of p38 mitogen-activated protein kinase.
Wilson KP, Fitzgibbon MJ, Caron PR, Griffith JP, Chen W, McCaffrey PG, Chambers SP, Su MS. Wilson KP, et al. J Biol Chem. 1996 Nov 1;271(44):27696-700. doi: 10.1074/jbc.271.44.27696. J Biol Chem. 1996. PMID: 8910361 Free article.
Structure and mechanism of interleukin-1 beta converting enzyme.
Wilson KP, Black JA, Thomson JA, Kim EE, Griffith JP, Navia MA, Murcko MA, Chambers SP, Aldape RA, Raybuck SA, et al. Wilson KP, et al. Nature. 1994 Jul 28;370(6487):270-5. doi: 10.1038/370270a0. Nature. 1994. PMID: 8035875
43 results