Barile E - Search Results

1

BI-69A11 enhances susceptibility of colon cancer cells to mda-7/IL-24-induced growth inhibition by targeting Akt.

Pal I, Sarkar S, Rajput S, Dey KK, Chakraborty S, Dash R, Das SK, Sarkar D, Barile E, De SK, Pellecchia M, Fisher PB, Mandal M. Pal I, et al. Among authors: barile e. Br J Cancer. 2014 Jul 8;111(1):101-11. doi: 10.1038/bjc.2014.227. Epub 2014 Jun 3. Br J Cancer. 2014. PMID: 24892445 Free PMC article.

2

Effective inhibition of melanoma by BI-69A11 is mediated by dual targeting of the AKT and NF-κB pathways.

Feng Y, Barile E, De SK, Stebbins JL, Cortez A, Aza-Blanc P, Villanueva J, Heryln M, Krajewski S, Pellecchia M, Ronai ZA, Chiang GG. Feng Y, et al. Among authors: barile e. Pigment Cell Melanoma Res. 2011 Aug;24(4):703-13. doi: 10.1111/j.1755-148X.2011.00867.x. Epub 2011 Jun 6. Pigment Cell Melanoma Res. 2011. PMID: 21592316 Free PMC article.

3

Inhibition of melanoma development in the Nras((Q61K)) ::Ink4a(-/-) mouse model by the small molecule BI-69A11.

Feng Y, Lau E, Scortegagna M, Ruller C, De SK, Barile E, Krajewski S, Aza-Blanc P, Williams R, Pinkerton AB, Jackson M, Chin L, Pellecchia M, Bosenberg M, Ronai ZA. Feng Y, et al. Among authors: barile e. Pigment Cell Melanoma Res. 2013 Jan;26(1):136-42. doi: 10.1111/pcmr.12033. Epub 2012 Nov 2. Pigment Cell Melanoma Res. 2013. PMID: 23035722 Free PMC article.

4

Synthesis and SAR studies of dual AKT/NF-κB inhibitors against melanoma.

Barile E, De SK, Feng Y, Chen V, Yang L, Ronai Z, Pellecchia M. Barile E, et al. Chem Biol Drug Des. 2013 Nov;82(5):520-533. doi: 10.1111/cbdd.12177. Epub 2013 Sep 25. Chem Biol Drug Des. 2013. PMID: 23790042 Free PMC article.

5

PDK1 inhibitors.

Barile E, De SK, Pellecchia M. Barile E, et al. Pharm Pat Anal. 2012 May;1(2):145-63. doi: 10.4155/ppa.12.17. Pharm Pat Anal. 2012. PMID: 24236780 Free PMC article. Review.

6

Design, synthesis and bioevaluation of an EphA2 receptor-based targeted delivery system.

Barile E, Wang S, Das SK, Noberini R, Dahl R, Stebbins JL, Pasquale EB, Fisher PB, Pellecchia M. Barile E, et al. ChemMedChem. 2014 Jul;9(7):1403-12. doi: 10.1002/cmdc.201400067. Epub 2014 Mar 26. ChemMedChem. 2014. PMID: 24677792 Free PMC article.

7

Design and Characterization of Novel EphA2 Agonists for Targeted Delivery of Chemotherapy to Cancer Cells.

Wu B, Wang S, De SK, Barile E, Quinn BA, Zharkikh I, Purves A, Stebbins JL, Oshima RG, Fisher PB, Pellecchia M. Wu B, et al. Among authors: barile e. Chem Biol. 2015 Jul 23;22(7):876-887. doi: 10.1016/j.chembiol.2015.06.011. Epub 2015 Jul 9. Chem Biol. 2015. PMID: 26165155 Free PMC article.

8

Therapy of pancreatic cancer via an EphA2 receptor-targeted delivery of gemcitabine.

Quinn BA, Wang S, Barile E, Das SK, Emdad L, Sarkar D, De SK, Morvaridi SK, Stebbins JL, Pandol SJ, Fisher PB, Pellecchia M. Quinn BA, et al. Among authors: barile e. Oncotarget. 2016 Mar 29;7(13):17103-10. doi: 10.18632/oncotarget.7931. Oncotarget. 2016. PMID: 26959746 Free PMC article.

9

NMR-based approaches for the identification and optimization of inhibitors of protein-protein interactions.

Barile E, Pellecchia M. Barile E, et al. Chem Rev. 2014 May 14;114(9):4749-63. doi: 10.1021/cr500043b. Epub 2014 Apr 8. Chem Rev. 2014. PMID: 24712885 Free PMC article. Review. No abstract available.

10

SBI-0640756 Attenuates the Growth of Clinically Unresponsive Melanomas by Disrupting the eIF4F Translation Initiation Complex.

Feng Y, Pinkerton AB, Hulea L, Zhang T, Davies MA, Grotegut S, Cheli Y, Yin H, Lau E, Kim H, De SK, Barile E, Pellecchia M, Bosenberg M, Li JL, James B, Hassig CA, Brown KM, Topisirovic I, Ronai ZA. Feng Y, et al. Among authors: barile e. Cancer Res. 2015 Dec 15;75(24):5211-8. doi: 10.1158/0008-5472.CAN-15-0885. Epub 2015 Nov 24. Cancer Res. 2015. PMID: 26603897 Free PMC article.

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