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Thrombospondin-1 induction in the diabetic myocardium stabilizes the cardiac matrix in addition to promoting vascular rarefaction through angiopoietin-2 upregulation.
Gonzalez-Quesada C, Cavalera M, Biernacka A, Kong P, Lee DW, Saxena A, Frunza O, Dobaczewski M, Shinde A, Frangogiannis NG. Gonzalez-Quesada C, et al. Among authors: frunza o. Circ Res. 2013 Dec 6;113(12):1331-44. doi: 10.1161/CIRCRESAHA.113.302593. Epub 2013 Sep 30. Circ Res. 2013. PMID: 24081879 Free PMC article.
Authors' Reply.
Frunza O, Russo I, Shinde AV, Su Y, Frangogiannis NG. Frunza O, et al. Am J Pathol. 2016 Aug;186(8):2234-2235. doi: 10.1016/j.ajpath.2016.06.001. Epub 2016 Jul 20. Am J Pathol. 2016. PMID: 27461365 Free PMC article.