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Filaggrin-stratified transcriptomic analysis of pediatric skin identifies mechanistic pathways in patients with atopic dermatitis.
Cole C, Kroboth K, Schurch NJ, Sandilands A, Sherstnev A, O'Regan GM, Watson RM, McLean WH, Barton GJ, Irvine AD, Brown SJ. Cole C, et al. Among authors: o regan gm. J Allergy Clin Immunol. 2014 Jul;134(1):82-91. doi: 10.1016/j.jaci.2014.04.021. Epub 2014 May 28. J Allergy Clin Immunol. 2014. PMID: 24880632 Free PMC article.
The role of filaggrin in the atopic diathesis.
O'Regan GM, Irvine AD. O'Regan GM, et al. Clin Exp Allergy. 2010 Jul;40(7):965-72. doi: 10.1111/j.1365-2222.2010.03522.x. Clin Exp Allergy. 2010. PMID: 20642575 Review.
Filaggrin in atopic dermatitis.
O'Regan GM, Sandilands A, McLean WHI, Irvine AD. O'Regan GM, et al. J Allergy Clin Immunol. 2008 Oct;122(4):689-693. doi: 10.1016/j.jaci.2008.08.002. Epub 2008 Sep 5. J Allergy Clin Immunol. 2008. PMID: 18774165 Review.
Filaggrin in atopic dermatitis.
O'Regan GM, Sandilands A, McLean WH, Irvine AD. O'Regan GM, et al. J Allergy Clin Immunol. 2009 Sep;124(3 Suppl 2):R2-6. doi: 10.1016/j.jaci.2009.07.013. J Allergy Clin Immunol. 2009. PMID: 19720209 Review.
Filaggrin loss-of-function mutations are associated with enhanced expression of IL-1 cytokines in the stratum corneum of patients with atopic dermatitis and in a murine model of filaggrin deficiency.
Kezic S, O'Regan GM, Lutter R, Jakasa I, Koster ES, Saunders S, Caspers P, Kemperman PM, Puppels GJ, Sandilands A, Chen H, Campbell LE, Kroboth K, Watson R, Fallon PG, McLean WH, Irvine AD. Kezic S, et al. J Allergy Clin Immunol. 2012 Apr;129(4):1031-9.e1. doi: 10.1016/j.jaci.2011.12.989. Epub 2012 Feb 8. J Allergy Clin Immunol. 2012. PMID: 22322004 Free PMC article.
South African amaXhosa patients with atopic dermatitis have decreased levels of filaggrin breakdown products but no loss-of-function mutations in filaggrin.
Thawer-Esmail F, Jakasa I, Todd G, Wen Y, Brown SJ, Kroboth K, Campbell LE, O'Regan GM, McLean WH, Irvine AD, Kezic S, Sandilands A. Thawer-Esmail F, et al. J Allergy Clin Immunol. 2014 Jan;133(1):280-2.e1-2. doi: 10.1016/j.jaci.2013.09.053. J Allergy Clin Immunol. 2014. PMID: 24369804 Free PMC article. No abstract available.
37 results