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High fat, high sucrose diet causes cardiac mitochondrial dysfunction due in part to oxidative post-translational modification of mitochondrial complex II.
Sverdlov AL, Elezaby A, Behring JB, Bachschmid MM, Luptak I, Tu VH, Siwik DA, Miller EJ, Liesa M, Shirihai OS, Pimentel DR, Cohen RA, Colucci WS. Sverdlov AL, et al. J Mol Cell Cardiol. 2015 Jan;78:165-73. doi: 10.1016/j.yjmcc.2014.07.018. Epub 2014 Aug 7. J Mol Cell Cardiol. 2015. PMID: 25109264 Free PMC article.
Mitochondrial remodeling in mice with cardiomyocyte-specific lipid overload.
Elezaby A, Sverdlov AL, Tu VH, Soni K, Luptak I, Qin F, Liesa M, Shirihai OS, Rimer J, Schaffer JE, Colucci WS, Miller EJ. Elezaby A, et al. Among authors: sverdlov al. J Mol Cell Cardiol. 2015 Feb;79:275-83. doi: 10.1016/j.yjmcc.2014.12.001. Epub 2014 Dec 9. J Mol Cell Cardiol. 2015. PMID: 25497302 Free PMC article.
Partial Liver Kinase B1 (LKB1) Deficiency Promotes Diastolic Dysfunction, De Novo Systolic Dysfunction, Apoptosis, and Mitochondrial Dysfunction With Dietary Metabolic Challenge.
Miller EJ, Calamaras T, Elezaby A, Sverdlov A, Qin F, Luptak I, Wang K, Sun X, Vijay A, Croteau D, Bachschmid M, Cohen RA, Walsh K, Colucci WS. Miller EJ, et al. J Am Heart Assoc. 2015 Dec 31;5(1):e002277. doi: 10.1161/JAHA.115.002277. J Am Heart Assoc. 2015. PMID: 26722122 Free PMC article.
Mitochondrial Reactive Oxygen Species Mediate Cardiac Structural, Functional, and Mitochondrial Consequences of Diet-Induced Metabolic Heart Disease.
Sverdlov AL, Elezaby A, Qin F, Behring JB, Luptak I, Calamaras TD, Siwik DA, Miller EJ, Liesa M, Shirihai OS, Pimentel DR, Cohen RA, Bachschmid MM, Colucci WS. Sverdlov AL, et al. J Am Heart Assoc. 2016 Jan 11;5(1):e002555. doi: 10.1161/JAHA.115.002555. J Am Heart Assoc. 2016. PMID: 26755553 Free PMC article.
Decreased ATP production and myocardial contractile reserve in metabolic heart disease.
Luptak I, Sverdlov AL, Panagia M, Qin F, Pimentel DR, Croteau D, Siwik DA, Ingwall JS, Bachschmid MM, Balschi JA, Colucci WS. Luptak I, et al. Among authors: sverdlov al. J Mol Cell Cardiol. 2018 Mar;116:106-114. doi: 10.1016/j.yjmcc.2018.01.017. Epub 2018 Feb 1. J Mol Cell Cardiol. 2018. PMID: 29409987 Free PMC article.
Overexpression of Catalase Diminishes Oxidative Cysteine Modifications of Cardiac Proteins.
Yao C, Behring JB, Shao D, Sverdlov AL, Whelan SA, Elezaby A, Yin X, Siwik DA, Seta F, Costello CE, Cohen RA, Matsui R, Colucci WS, McComb ME, Bachschmid MM. Yao C, et al. Among authors: sverdlov al. PLoS One. 2015 Dec 7;10(12):e0144025. doi: 10.1371/journal.pone.0144025. eCollection 2015. PLoS One. 2015. PMID: 26642319 Free PMC article.
118 results