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Annonacin, a natural lipophilic mitochondrial complex I inhibitor, increases phosphorylation of tau in the brain of FTDP-17 transgenic mice.
Yamada ES, Respondek G, Müssner S, de Andrade A, Höllerhage M, Depienne C, Rastetter A, Tarze A, Friguet B, Salama M, Champy P, Oertel WH, Höglinger GU. Yamada ES, et al. Among authors: de andrade a. Exp Neurol. 2014 Mar;253:113-25. doi: 10.1016/j.expneurol.2013.12.017. Epub 2014 Jan 3. Exp Neurol. 2014. PMID: 24389273 Free article.
Piericidin A aggravates Tau pathology in P301S transgenic mice.
Höllerhage M, Deck R, De Andrade A, Respondek G, Xu H, Rösler TW, Salama M, Carlsson T, Yamada ES, Gad El Hak SA, Goedert M, Oertel WH, Höglinger GU. Höllerhage M, et al. Among authors: de andrade a. PLoS One. 2014 Dec 1;9(12):e113557. doi: 10.1371/journal.pone.0113557. eCollection 2014. PLoS One. 2014. PMID: 25437199 Free PMC article.
Tau silencing by siRNA in the P301S mouse model of tauopathy.
Xu H, Rösler TW, Carlsson T, de Andrade A, Fiala O, Hollerhage M, Oertel WH, Goedert M, Aigner A, Höglinger GU. Xu H, et al. Among authors: de andrade a. Curr Gene Ther. 2014;14(5):343-51. doi: 10.2174/156652321405140926160602. Curr Gene Ther. 2014. PMID: 25687501
PERK activation mitigates tau pathology in vitro and in vivo.
Bruch J, Xu H, Rösler TW, De Andrade A, Kuhn PH, Lichtenthaler SF, Arzberger T, Winklhofer KF, Müller U, Höglinger GU. Bruch J, et al. Among authors: de andrade a. EMBO Mol Med. 2017 Mar;9(3):371-384. doi: 10.15252/emmm.201606664. EMBO Mol Med. 2017. PMID: 28148553 Free PMC article.
A brain-specific isoform of mitochondrial apoptosis-inducing factor: AIF2.
Hangen E, De Zio D, Bordi M, Zhu C, Dessen P, Caffin F, Lachkar S, Perfettini JL, Lazar V, Benard J, Fimia GM, Piacentini M, Harper F, Pierron G, Vicencio JM, Bénit P, de Andrade A, Höglinger G, Culmsee C, Rustin P, Blomgren K, Cecconi F, Kroemer G, Modjtahedi N. Hangen E, et al. Among authors: de andrade a, de zio d. Cell Death Differ. 2010 Jul;17(7):1155-66. doi: 10.1038/cdd.2009.211. Epub 2010 Jan 29. Cell Death Differ. 2010. PMID: 20111043 Free article.
658 results