AMPK controls exercise endurance, mitochondrial oxidative capacity, and skeletal muscle integrity.
Lantier L, Fentz J, Mounier R, Leclerc J, Treebak JT, Pehmøller C, Sanz N, Sakakibara I, Saint-Amand E, Rimbaud S, Maire P, Marette A, Ventura-Clapier R, Ferry A, Wojtaszewski JF, Foretz M, Viollet B.
Lantier L, et al. Among authors: sakakibara i.
FASEB J. 2014 Jul;28(7):3211-24. doi: 10.1096/fj.14-250449. Epub 2014 Mar 20.
FASEB J. 2014.
PMID: 24652947
However, the lack of skeletal muscle AMPK diminished maximal ADP-stimulated mitochondrial respiration, showing an impairment at complex I. This effect was not accompanied by changes in mitochondrial number, indicating that AMPK regulates muscle metabolic adaptation through …
However, the lack of skeletal muscle AMPK diminished maximal ADP-stimulated mitochondrial respiration, showing an impairment at complex I …