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Page 1
Variation of the net charge, lipophilicity, and side chain flexibility in Dmt(1)-DALDA: Effect on Opioid Activity and Biodistribution.
Novoa A, Van Dorpe S, Wynendaele E, Spetea M, Bracke N, Stalmans S, Betti C, Chung NN, Lemieux C, Zuegg J, Cooper MA, Tourwé D, De Spiegeleer B, Schiller PW, Ballet S. Novoa A, et al. Among authors: betti c. J Med Chem. 2012 Nov 26;55(22):9549-61. doi: 10.1021/jm3008079. Epub 2012 Nov 12. J Med Chem. 2012. PMID: 23102273 Free PMC article.
Dual Alleviation of Acute and Neuropathic Pain by Fused Opioid Agonist-Neurokinin 1 Antagonist Peptidomimetics.
Betti C, Starnowska J, Mika J, Dyniewicz J, Frankiewicz L, Novoa A, Bochynska M, Keresztes A, Kosson P, Makuch W, Van Duppen J, Chung NN, Vanden Broeck J, Lipkowski AW, Schiller PW, Janssens F, Ceusters M, Sommen F, Meert T, Przewlocka B, Tourwé D, Ballet S. Betti C, et al. ACS Med Chem Lett. 2015 Oct 31;6(12):1209-14. doi: 10.1021/acsmedchemlett.5b00359. eCollection 2015 Dec 10. ACS Med Chem Lett. 2015. PMID: 26713106 Free PMC article.
χ-Space Screening of Dermorphin-Based Tetrapeptides through Use of Constrained Arylazepinone and Quinolinone Scaffolds.
Van der Poorten O, Van Den Hauwe R, Eiselt E, Betti C, Guillemyn K, Chung NN, Hallé F, Bihel F, Schiller PW, Tourwé D, Sarret P, Gendron L, Ballet S. Van der Poorten O, et al. Among authors: betti c. ACS Med Chem Lett. 2017 Oct 4;8(11):1177-1182. doi: 10.1021/acsmedchemlett.7b00347. eCollection 2017 Nov 9. ACS Med Chem Lett. 2017. PMID: 29152051 Free PMC article.
Structural basis for bifunctional peptide recognition at human δ-opioid receptor.
Fenalti G, Zatsepin NA, Betti C, Giguere P, Han GW, Ishchenko A, Liu W, Guillemyn K, Zhang H, James D, Wang D, Weierstall U, Spence JC, Boutet S, Messerschmidt M, Williams GJ, Gati C, Yefanov OM, White TA, Oberthuer D, Metz M, Yoon CH, Barty A, Chapman HN, Basu S, Coe J, Conrad CE, Fromme R, Fromme P, Tourwé D, Schiller PW, Roth BL, Ballet S, Katritch V, Stevens RC, Cherezov V. Fenalti G, et al. Among authors: betti c. Nat Struct Mol Biol. 2015 Mar;22(3):265-8. doi: 10.1038/nsmb.2965. Epub 2015 Feb 16. Nat Struct Mol Biol. 2015. PMID: 25686086 Free PMC article.
Neurotensin Analogues Containing Cyclic Surrogates of Tyrosine at Position 11 Improve NTS2 Selectivity Leading to Analgesia without Hypotension and Hypothermia.
Eiselt E, Gonzalez S, Martin C, Chartier M, Betti C, Longpré JM, Cavelier F, Tourwé D, Gendron L, Ballet S, Sarret P. Eiselt E, et al. Among authors: betti c. ACS Chem Neurosci. 2019 Nov 20;10(11):4535-4544. doi: 10.1021/acschemneuro.9b00390. Epub 2019 Oct 21. ACS Chem Neurosci. 2019. PMID: 31589400
98 results