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Upregulation of adenosine A1 receptors facilitates sinoatrial node dysfunction in chronic canine heart failure by exacerbating nodal conduction abnormalities revealed by novel dual-sided intramural optical mapping.
Lou Q, Hansen BJ, Fedorenko O, Csepe TA, Kalyanasundaram A, Li N, Hage LT, Glukhov AV, Billman GE, Weiss R, Mohler PJ, Györke S, Biesiadecki BJ, Carnes CA, Fedorov VV. Lou Q, et al. Among authors: hage lt. Circulation. 2014 Jul 22;130(4):315-24. doi: 10.1161/CIRCULATIONAHA.113.007086. Epub 2014 May 16. Circulation. 2014. PMID: 24838362 Free PMC article.
Sinoatrial node reentry in a canine chronic left ventricular infarct model: role of intranodal fibrosis and heterogeneity of refractoriness.
Glukhov AV, Hage LT, Hansen BJ, Pedraza-Toscano A, Vargas-Pinto P, Hamlin RL, Weiss R, Carnes CA, Billman GE, Fedorov VV. Glukhov AV, et al. Among authors: hage lt. Circ Arrhythm Electrophysiol. 2013 Oct;6(5):984-94. doi: 10.1161/CIRCEP.113.000404. Epub 2013 Aug 19. Circ Arrhythm Electrophysiol. 2013. PMID: 23960214 Free PMC article.
Calsequestrin 2 deletion causes sinoatrial node dysfunction and atrial arrhythmias associated with altered sarcoplasmic reticulum calcium cycling and degenerative fibrosis within the mouse atrial pacemaker complex1.
Glukhov AV, Kalyanasundaram A, Lou Q, Hage LT, Hansen BJ, Belevych AE, Mohler PJ, Knollmann BC, Periasamy M, Györke S, Fedorov VV. Glukhov AV, et al. Among authors: hage lt. Eur Heart J. 2015 Mar 14;36(11):686-97. doi: 10.1093/eurheartj/eht452. Epub 2013 Nov 11. Eur Heart J. 2015. PMID: 24216388 Free PMC article.