Gulick AM - Search Results

1

Identification of inhibitors of PvdQ, an enzyme involved in the synthesis of the siderophore pyoverdine.

Wurst JM, Drake EJ, Theriault JR, Jewett IT, VerPlank L, Perez JR, Dandapani S, Palmer M, Moskowitz SM, Schreiber SL, Munoz B, Gulick AM. Wurst JM, et al. Among authors: gulick am. ACS Chem Biol. 2014 Jul 18;9(7):1536-44. doi: 10.1021/cb5001586. Epub 2014 May 21. ACS Chem Biol. 2014. PMID: 24824984 Free PMC article.

2

Structural advances toward understanding the catalytic activity and conformational dynamics of modular nonribosomal peptide synthetases.

Patel KD, MacDonald MR, Ahmed SF, Singh J, Gulick AM. Patel KD, et al. Among authors: gulick am. Nat Prod Rep. 2023 Sep 20;40(9):1550-1582. doi: 10.1039/d3np00003f. Nat Prod Rep. 2023. PMID: 37114973 Free PMC article. Review.

3

Structure of the EntB multidomain nonribosomal peptide synthetase and functional analysis of its interaction with the EntE adenylation domain.

Drake EJ, Nicolai DA, Gulick AM. Drake EJ, et al. Among authors: gulick am. Chem Biol. 2006 Apr;13(4):409-19. doi: 10.1016/j.chembiol.2006.02.005. Chem Biol. 2006. PMID: 16632253

4

The 1.8 A crystal structure of PA2412, an MbtH-like protein from the pyoverdine cluster of Pseudomonas aeruginosa.

Drake EJ, Cao J, Qu J, Shah MB, Straubinger RM, Gulick AM. Drake EJ, et al. Among authors: gulick am. J Biol Chem. 2007 Jul 13;282(28):20425-34. doi: 10.1074/jbc.M611833200. Epub 2007 May 14. J Biol Chem. 2007. PMID: 17502378 Free article.

5

Three-dimensional structures of Pseudomonas aeruginosa PvcA and PvcB, two proteins involved in the synthesis of 2-isocyano-6,7-dihydroxycoumarin.

Drake EJ, Gulick AM. Drake EJ, et al. Among authors: gulick am. J Mol Biol. 2008 Dec 5;384(1):193-205. doi: 10.1016/j.jmb.2008.09.027. Epub 2008 Sep 19. J Mol Biol. 2008. PMID: 18824174 Free PMC article.

6

Biochemical and structural characterization of bisubstrate inhibitors of BasE, the self-standing nonribosomal peptide synthetase adenylate-forming enzyme of acinetobactin synthesis.

Drake EJ, Duckworth BP, Neres J, Aldrich CC, Gulick AM. Drake EJ, et al. Among authors: gulick am. Biochemistry. 2010 Nov 2;49(43):9292-305. doi: 10.1021/bi101226n. Biochemistry. 2010. PMID: 20853905 Free PMC article.

7

Structural characterization and high-throughput screening of inhibitors of PvdQ, an NTN hydrolase involved in pyoverdine synthesis.

Drake EJ, Gulick AM. Drake EJ, et al. Among authors: gulick am. ACS Chem Biol. 2011 Nov 18;6(11):1277-86. doi: 10.1021/cb2002973. Epub 2011 Sep 15. ACS Chem Biol. 2011. PMID: 21892836 Free PMC article.

8

Rational design of proteolytically stable, cell-permeable peptide-based selective Mcl-1 inhibitors.

Muppidi A, Doi K, Edwardraja S, Drake EJ, Gulick AM, Wang HG, Lin Q. Muppidi A, et al. Among authors: gulick am. J Am Chem Soc. 2012 Sep 12;134(36):14734-7. doi: 10.1021/ja306864v. Epub 2012 Sep 4. J Am Chem Soc. 2012. PMID: 22920569 Free PMC article.

9

Non-nucleoside inhibitors of BasE, an adenylating enzyme in the siderophore biosynthetic pathway of the opportunistic pathogen Acinetobacter baumannii.

Neres J, Engelhart CA, Drake EJ, Wilson DJ, Fu P, Boshoff HI, Barry CE 3rd, Gulick AM, Aldrich CC. Neres J, et al. Among authors: gulick am. J Med Chem. 2013 Mar 28;56(6):2385-405. doi: 10.1021/jm301709s. Epub 2013 Mar 13. J Med Chem. 2013. PMID: 23437866 Free PMC article.

10

Structure-based engineering of streptavidin monomer with a reduced biotin dissociation rate.

Demonte D, Drake EJ, Lim KH, Gulick AM, Park S. Demonte D, et al. Among authors: gulick am. Proteins. 2013 Sep;81(9):1621-33. doi: 10.1002/prot.24320. Epub 2013 Jun 17. Proteins. 2013. PMID: 23670729

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