Yang Q - Search Results

1

Discovery of 1-aryloxyethyl piperazine derivatives as Kv1.5 potassium channel inhibitors (part I).

Guo X, Ma X, Yang Q, Xu J, Huang L, Jia J, Shan J, Liu L, Chen W, Chu H, Wei J, Zhang X, Sun H, Tang Y, You Q. Guo X, et al. Among authors: yang q. Eur J Med Chem. 2014 Jun 23;81:89-94. doi: 10.1016/j.ejmech.2014.03.075. Epub 2014 Mar 28. Eur J Med Chem. 2014. PMID: 24824064

2

Design and bio-evaluation of indole derivatives as potent Kv1.5 inhibitors.

Guo X, Yang Q, Xu J, Zhang L, Chu H, Yu P, Zhu Y, Wei J, Chen W, Zhang Y, Zhang X, Sun H, Tang Y, You Q. Guo X, et al. Among authors: yang q. Bioorg Med Chem. 2013 Nov 1;21(21):6466-76. doi: 10.1016/j.bmc.2013.08.041. Epub 2013 Aug 31. Bioorg Med Chem. 2013. PMID: 24071446

3

Design, synthesis, and biological evaluation of arylmethylpiperidines as Kv1.5 potassium channel inhibitors.

Zhao L, Yang Q, Tang Y, You Q, Guo X. Zhao L, et al. Among authors: yang q. J Enzyme Inhib Med Chem. 2022 Dec;37(1):462-471. doi: 10.1080/14756366.2021.2018683. J Enzyme Inhib Med Chem. 2022. PMID: 35012386 Free PMC article.

4

Modeling the binding modes of Kv1.5 potassium channel and blockers.

Yang Q, Du L, Wang X, Li M, You Q. Yang Q, et al. J Mol Graph Model. 2008 Sep;27(2):178-87. doi: 10.1016/j.jmgm.2008.04.002. Epub 2008 Apr 10. J Mol Graph Model. 2008. PMID: 18485768

5

Drug discoveries towards Kv1.5 potassium channel.

Yang Q, Wang X, Du L, Li M, You Q. Yang Q, et al. Curr Top Med Chem. 2009;9(4):339-47. doi: 10.2174/156802609788317810. Curr Top Med Chem. 2009. PMID: 19442205

6

Discovery of a novel series of quinolone and naphthyridine derivatives as potential topoisomerase I inhibitors by scaffold modification.

You QD, Li ZY, Huang CH, Yang Q, Wang XJ, Guo QL, Chen XG, He XG, Li TK, Chern JW. You QD, et al. Among authors: yang q. J Med Chem. 2009 Sep 24;52(18):5649-61. doi: 10.1021/jm900469e. J Med Chem. 2009. PMID: 19715319

7

[The research practice of anti-arrhythmic agents targeting on potassium ion channel].

Yang Q, Wang XJ, Tang YQ, You QD. Yang Q, et al. Yao Xue Xue Bao. 2011 Jan;46(1):12-8. Yao Xue Xue Bao. 2011. PMID: 21465803 Review. Chinese.

8

Studies on gambogic acid (IV): Exploring structure-activity relationship with IκB kinase-beta (IKKβ).

Sun H, Chen F, Wang X, Liu Z, Yang Q, Zhang X, Zhu J, Qiang L, Guo Q, You Q. Sun H, et al. Among authors: yang q. Eur J Med Chem. 2012 May;51:110-23. doi: 10.1016/j.ejmech.2012.02.029. Epub 2012 Mar 3. Eur J Med Chem. 2012. PMID: 22472167

9

Antiarrhythmic efficacy of CPUY102122, a multiple ion channel blocker, on rabbits with ischemia/reperfusion injury.

Wang M, Shan J, Yang Q, Ma X, Jin S, Guo X, You Q, Tang Y. Wang M, et al. Among authors: yang q. Pharmacol Rep. 2014 Dec;66(6):1022-30. doi: 10.1016/j.pharep.2014.06.017. Epub 2014 Jul 3. Pharmacol Rep. 2014. PMID: 25443730

10

Molecular hybridization, synthesis, and biological evaluation of novel chroman I(Kr) and I(Ks) dual blockers.

Du L, Li M, Yang Q, Tang Y, You Q, Xia L. Du L, et al. Among authors: yang q. Bioorg Med Chem Lett. 2009 Mar 1;19(5):1477-80. doi: 10.1016/j.bmcl.2009.01.022. Epub 2009 Jan 14. Bioorg Med Chem Lett. 2009. PMID: 19185489

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