Jia J - Search Results

1

Discovery of 1-aryloxyethyl piperazine derivatives as Kv1.5 potassium channel inhibitors (part I).

Guo X, Ma X, Yang Q, Xu J, Huang L, Jia J, Shan J, Liu L, Chen W, Chu H, Wei J, Zhang X, Sun H, Tang Y, You Q. Guo X, et al. Among authors: jia j. Eur J Med Chem. 2014 Jun 23;81:89-94. doi: 10.1016/j.ejmech.2014.03.075. Epub 2014 Mar 28. Eur J Med Chem. 2014. PMID: 24824064

2

Novel IKKβ inhibitors discovery based on the co-crystal structure by using binding-conformation-based and ligand-based method.

Huang JJ, Wu XW, Jia JM, Guo XK, Xue X, Jiang ZY, Zhang SL, Zhang XJ, Sun HP, You QD. Huang JJ, et al. Eur J Med Chem. 2013 May;63:269-78. doi: 10.1016/j.ejmech.2013.01.045. Epub 2013 Feb 17. Eur J Med Chem. 2013. PMID: 23501112

3

Synthesis and bioevaluation of a series of α-pyrone derivatives as potent activators of Nrf2/ARE pathway (part I).

Xi MY, Sun ZY, Sun HP, Jia JM, Jiang ZY, Tao L, Ye M, Yang X, Wang YJ, Xue X, Huang JJ, Gao Y, Guo XK, Zhang SL, Yang YR, Guo QL, Hu R, You QD. Xi MY, et al. Eur J Med Chem. 2013 Aug;66:364-71. doi: 10.1016/j.ejmech.2013.06.007. Epub 2013 Jun 14. Eur J Med Chem. 2013. PMID: 23820128

4

3-aroylmethylene-2,3,6,7-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4(11bH)-ones as potent Nrf2/ARE inducers in human cancer cells and AOM-DSS treated mice.

Xi MY, Jia JM, Sun HP, Sun ZY, Jiang JW, Wang YJ, Zhang MY, Zhu JF, Xu LL, Jiang ZY, Xue X, Ye M, Yang X, Gao Y, Tao L, Guo XK, Xu XL, Guo QL, Zhang XJ, Hu R, You QD. Xi MY, et al. J Med Chem. 2013 Oct 24;56(20):7925-38. doi: 10.1021/jm400944k. Epub 2013 Oct 9. J Med Chem. 2013. PMID: 24053646

5

Synthesis and evaluation of a novel class Hsp90 inhibitors containing 1-phenylpiperazine scaffold.

Jia JM, Liu F, Xu XL, Guo XK, Jiang F, Cherfaoui B, Sun HP, You QD. Jia JM, et al. Bioorg Med Chem Lett. 2014 Mar 15;24(6):1557-61. doi: 10.1016/j.bmcl.2014.01.070. Epub 2014 Feb 15. Bioorg Med Chem Lett. 2014. PMID: 24582477

6

Identification and optimization of novel Hsp90 inhibitors with tetrahydropyrido[4,3-d]pyrimidines core through shape-based screening.

Sun HP, Jia JM, Jiang F, Xu XL, Liu F, Guo XK, Cherfaoui B, Huang HZ, Pan Y, You QD. Sun HP, et al. Eur J Med Chem. 2014 May 22;79:399-412. doi: 10.1016/j.ejmech.2014.03.061. Epub 2014 Mar 21. Eur J Med Chem. 2014. PMID: 24763261

7

Novel Tetrahydropyrido[4,3-d]pyrimidines as Potent Inhibitors of Chaperone Heat Shock Protein 90.

Jiang F, Wang HJ, Jin YH, Zhang Q, Wang ZH, Jia JM, Liu F, Wang L, Bao QC, Li DD, You QD, Xu XL. Jiang F, et al. J Med Chem. 2016 Dec 8;59(23):10498-10519. doi: 10.1021/acs.jmedchem.6b00912. Epub 2016 Nov 22. J Med Chem. 2016. PMID: 27933959

8

Identification, design and bio-evaluation of novel Hsp90 inhibitors by ligand-based virtual screening.

Jia J, Xu X, Liu F, Guo X, Zhang M, Lu M, Xu L, Wei J, Zhu J, Zhang S, Zhang S, Sun H, You Q. Jia J, et al. PLoS One. 2013;8(4):e59315. doi: 10.1371/journal.pone.0059315. Epub 2013 Apr 2. PLoS One. 2013. PMID: 23565147 Free PMC article.

9

Indenoisoquinoline derivatives as topoisomerase I inhibitors that suppress angiogenesis by affecting the HIF signaling pathway.

Xu X, Liu F, Zhang S, Jia J, Li Z, Guo X, Yang Y, Sun H, You Q. Xu X, et al. Among authors: jia j. Biomed Pharmacother. 2013 Oct;67(8):715-22. doi: 10.1016/j.biopha.2013.06.004. Epub 2013 Jul 4. Biomed Pharmacother. 2013. PMID: 23932721

10

Discovery and design of tricyclic scaffolds as protein kinase CK2 (CK2) inhibitors through a combination of shape-based virtual screening and structure-based molecular modification.

Sun H, Xu X, Wu X, Zhang X, Liu F, Jia J, Guo X, Huang J, Jiang Z, Feng T, Chu H, Zhou Y, Zhang S, Liu Z, You Q. Sun H, et al. Among authors: jia j. J Chem Inf Model. 2013 Aug 26;53(8):2093-102. doi: 10.1021/ci400114f. Epub 2013 Aug 12. J Chem Inf Model. 2013. PMID: 23937544

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