The effect of folic acid deficiency on FGF pathway via Brachyury regulation in neural tube defects.
Chang S, Lu X, Wang S, Wang Z, Huo J, Huang J, Shangguan S, Li S, Zou J, Bao Y, Guo J, Wang F, Niu B, Zhang T, Qiu Z, Wu J, Wang L.
Chang S, et al. Among authors: qiu z.
FASEB J. 2019 Apr;33(4):4688-4702. doi: 10.1096/fj.201801536R. Epub 2018 Dec 28.
FASEB J. 2019.
PMID: 30592646
Taken together, our findings highlight the effect of FA on FGF pathways during neurogenesis, and the mechanism may be due to the low expression of Brachyury gene via hypermethylation under FA-insufficient conditions.-Chang, S., Lu, X., Wang, S., Wang, Z., Huo, J., Huang, J …
Taken together, our findings highlight the effect of FA on FGF pathways during neurogenesis, and the mechanism may be due to the low express …