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Synthesis, biological, and biophysical studies of DAG-indololactones designed as selective activators of RasGRP.
Garcia LC, Donadío LG, Mann E, Kolusheva S, Kedei N, Lewin NE, Hill CS, Kelsey JS, Yang J, Esch TE, Santos M, Peach ML, Kelley JA, Blumberg PM, Jelinek R, Marquez VE, Comin MJ. Garcia LC, et al. Among authors: comin mj. Bioorg Med Chem. 2014 Jun 15;22(12):3123-40. doi: 10.1016/j.bmc.2014.04.024. Epub 2014 Apr 20. Bioorg Med Chem. 2014. PMID: 24794745 Free PMC article.
Conformationally constrained analogues of diacylglycerol (DAG). 31. Modulation of the biological properties of diacylgycerol lactones (DAG-lactones) containing rigid-rod acyl groups separated from the core lactone by spacer units of different lengths.
Comin MJ, Czifra G, Kedei N, Telek A, Lewin NE, Kolusheva S, Velasquez JF, Kobylarz R, Jelinek R, Blumberg PM, Marquez VE. Comin MJ, et al. J Med Chem. 2009 May 28;52(10):3274-83. doi: 10.1021/jm900186m. J Med Chem. 2009. PMID: 19379015 Free PMC article.
24 results