Chen L - Search Results

1

A rational design strategy of the novel topoisomerase II inhibitors for the synthesis of the 4-O-(2-pyrazinecarboxylic)-4'-demethylepipodophyllotoxin with antitumor activity by diminishing the relaxation reaction of topoisomerase II-DNA decatenation.

Zhao W, Chen L, Li HM, Wang DJ, Li DS, Chen T, Yuan ZP, Tang YJ. Zhao W, et al. Among authors: chen l, chen t. Bioorg Med Chem. 2014 Jun 1;22(11):2998-3007. doi: 10.1016/j.bmc.2014.03.048. Epub 2014 Apr 13. Bioorg Med Chem. 2014. PMID: 24775914

2

Synthesis and bioactivity of tripolinolate A from Tripolium vulgare and its analogs.

Chen L, Liang Y, Song T, Anjum K, Wang W, Yu S, Huang H, Lian XY, Zhang Z. Chen L, et al. Bioorg Med Chem Lett. 2015 Jul 1;25(13):2629-33. doi: 10.1016/j.bmcl.2015.04.091. Epub 2015 May 6. Bioorg Med Chem Lett. 2015. PMID: 25981689

3

Anti-colorectal cancer effects of tripolinolate A from Tripolium vulgare.

Chen L, Wang WL, Song TF, Xie X, Ye XW, Liang Y, Huang HC, Yan SL, Lian XY, Zhang ZZ. Chen L, et al. Chin J Nat Med. 2017 Aug;15(8):576-583. doi: 10.1016/S1875-5364(17)30085-7. Chin J Nat Med. 2017. PMID: 28939020

4

A novel compound LingH2-10 inhibits the growth of triple negative breast cancer cells in vitro and in vivo as a selective inverse agonist of estrogen-related receptor α.

Ning Y, Chen H, Du Y, Ling H, Zhang L, Chen L, Qi H, Shi X, Li Q. Ning Y, et al. Among authors: chen l, chen h. Biomed Pharmacother. 2017 Sep;93:913-922. doi: 10.1016/j.biopha.2017.07.016. Epub 2017 Jul 13. Biomed Pharmacother. 2017. PMID: 28715872

5

Polyoxygenated 24,28-epoxyergosterols inhibiting the proliferation of glioma cells from sea anemone Anthopleura midori.

Yu S, Ye X, Chen L, Lian XY, Zhang Z. Yu S, et al. Among authors: chen l. Steroids. 2014 Oct;88:19-25. doi: 10.1016/j.steroids.2014.06.013. Epub 2014 Jun 26. Steroids. 2014. PMID: 24973636

6

Bioactive Polycyclic Quinones from Marine Streptomyces sp. 182SMLY.

Liang Y, Xie X, Chen L, Yan S, Ye X, Anjum K, Huang H, Lian X, Zhang Z. Liang Y, et al. Among authors: chen l. Mar Drugs. 2016 Jan 6;14(1):10. doi: 10.3390/md14010010. Mar Drugs. 2016. PMID: 26751456 Free PMC article.

7

Cytotoxic and anti-colorectal tumor effects of sulfated saponins from sea cucumber Holothuria moebii.

Yu S, Ye X, Chen L, Xie X, Zhou Q, Lian XY, Zhang Z. Yu S, et al. Among authors: chen l. Phytomedicine. 2015 Nov 15;22(12):1112-9. doi: 10.1016/j.phymed.2015.08.007. Epub 2015 Aug 28. Phytomedicine. 2015. PMID: 26547534

8

A unique indolizinium alkaloid streptopertusacin A and bioactive bafilomycins from marine-derived Streptomyces sp. HZP-2216E.

Zhang X, Chen L, Chai W, Lian XY, Zhang Z. Zhang X, et al. Among authors: chen l. Phytochemistry. 2017 Dec;144:119-126. doi: 10.1016/j.phytochem.2017.09.010. Epub 2017 Sep 17. Phytochemistry. 2017. PMID: 28923323

9

Characterization of a selective inverse agonist for estrogen related receptor α as a potential agent for breast cancer.

Zhang L, Liu P, Chen H, Li Q, Chen L, Qi H, Shi X, Du Y. Zhang L, et al. Among authors: chen l, chen h. Eur J Pharmacol. 2016 Oct 15;789:439-448. doi: 10.1016/j.ejphar.2016.08.008. Epub 2016 Aug 4. Eur J Pharmacol. 2016. PMID: 27498368

10

Naringenin exerts anti-angiogenic effects in human endothelial cells: Involvement of ERRα/VEGF/KDR signaling pathway.

Li Q, Wang Y, Zhang L, Chen L, Du Y, Ye T, Shi X. Li Q, et al. Among authors: chen l. Fitoterapia. 2016 Jun;111:78-86. doi: 10.1016/j.fitote.2016.04.015. Epub 2016 Apr 20. Fitoterapia. 2016. PMID: 27105956

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