Dohnal V - Search Results

1

Preparation, in vitro screening and molecular modelling of monoquaternary compounds related to the selective acetylcholinesterase inhibitor BW284c51.

Benek O, Musilek K, Horova A, Dohnal V, Dolezal R, Kuca K. Benek O, et al. Among authors: dohnal v. Med Chem. 2014;11(1):21-9. doi: 10.2174/1573406410666140428153110. Med Chem. 2014. PMID: 24773345

2

Monoquaternary pyridinium salts with modified side chain-synthesis and evaluation on model of tabun- and paraoxon-inhibited acetylcholinesterase.

Musilek K, Kucera J, Jun D, Dohnal V, Opletalova V, Kuca K. Musilek K, et al. Among authors: dohnal v. Bioorg Med Chem. 2008 Sep 1;16(17):8218-23. doi: 10.1016/j.bmc.2008.07.036. Epub 2008 Jul 20. Bioorg Med Chem. 2008. PMID: 18676153

3

Synthesis and in vitro evaluation of N-alkyl-7-methoxytacrine hydrochlorides as potential cholinesterase inhibitors in Alzheimer disease.

Korabecny J, Musilek K, Holas O, Binder J, Zemek F, Marek J, Pohanka M, Opletalova V, Dohnal V, Kuca K. Korabecny J, et al. Among authors: dohnal v. Bioorg Med Chem Lett. 2010 Oct 15;20(20):6093-5. doi: 10.1016/j.bmcl.2010.08.044. Epub 2010 Aug 16. Bioorg Med Chem Lett. 2010. PMID: 20817518

4

Preparation, in vitro screening and molecular modelling of symmetrical 4-tert-butylpyridinium cholinesterase inhibitors--analogues of SAD-128.

Musilek K, Roder J, Komloova M, Holas O, Hrabinova M, Pohanka M, Dohnal V, Opletalova V, Kuca K, Jung YS. Musilek K, et al. Among authors: dohnal v. Bioorg Med Chem Lett. 2011 Jan 1;21(1):150-4. doi: 10.1016/j.bmcl.2010.11.051. Epub 2010 Nov 16. Bioorg Med Chem Lett. 2011. PMID: 21144749

5

Mono-oxime bisquaternary acetylcholinesterase reactivators with prop-1,3-diyl linkage-Preparation, in vitro screening and molecular docking.

Musilek K, Komloova M, Holas O, Horova A, Pohanka M, Gunn-Moore F, Dohnal V, Dolezal M, Kuca K. Musilek K, et al. Among authors: dohnal v. Bioorg Med Chem. 2011 Jan 15;19(2):754-62. doi: 10.1016/j.bmc.2010.12.021. Epub 2010 Dec 16. Bioorg Med Chem. 2011. PMID: 21215642

6

Preparation and in vitro screening of symmetrical bis-isoquinolinium cholinesterase inhibitors bearing various connecting linkage--implications for early Myasthenia gravis treatment.

Musilek K, Komloova M, Holas O, Hrabinova M, Pohanka M, Dohnal V, Nachon F, Dolezal M, Kuca K. Musilek K, et al. Among authors: dohnal v. Eur J Med Chem. 2011 Feb;46(2):811-8. doi: 10.1016/j.ejmech.2010.12.011. Epub 2010 Dec 21. Eur J Med Chem. 2011. PMID: 21236521

7

Preparation, in vitro screening and molecular modelling of symmetrical bis-quinolinium cholinesterase inhibitors--implications for early myasthenia gravis treatment.

Komloova M, Musilek K, Horova A, Holas O, Dohnal V, Gunn-Moore F, Kuca K. Komloova M, et al. Among authors: dohnal v. Bioorg Med Chem Lett. 2011 Apr 15;21(8):2505-9. doi: 10.1016/j.bmcl.2011.02.047. Epub 2011 Feb 21. Bioorg Med Chem Lett. 2011. PMID: 21397501

8

The preparation, in vitro screening and molecular docking of symmetrical bisquaternary cholinesterase inhibitors containing a but-(2E)-en-1,4-diyl connecting linkage.

Musilek K, Pavlikova R, Marek J, Komloova M, Holas O, Hrabinova M, Pohanka M, Dohnal V, Dolezal M, Gunn-Moore F, Kuca K. Musilek K, et al. Among authors: dohnal v. J Enzyme Inhib Med Chem. 2011 Apr;26(2):245-53. doi: 10.3109/14756366.2010.496362. J Enzyme Inhib Med Chem. 2011. PMID: 21406034 Free article.

9

Monooxime Bispyridinium Reactivators Bearing Xylene Linker Synthesis and In Vitro Evaluation on Model of Organophosphate-Inhibited Acetylcholinesterase.

Musilek K, Hambalek J, Holas O, Dohnal V, Kuca K. Musilek K, et al. Among authors: dohnal v. Med Chem. 2016;12(4):362-70. doi: 10.2174/1573406411666151002125640. Med Chem. 2016. PMID: 26427931

10

Design, synthesis and in vitro evaluation of benzothiazole-based ureas as potential ABAD/17β-HSD10 modulators for Alzheimer's disease treatment.

Hroch L, Benek O, Guest P, Aitken L, Soukup O, Janockova J, Musil K, Dohnal V, Dolezal R, Kuca K, Smith TK, Gunn-Moore F, Musilek K. Hroch L, et al. Among authors: dohnal v. Bioorg Med Chem Lett. 2016 Aug 1;26(15):3675-8. doi: 10.1016/j.bmcl.2016.05.087. Epub 2016 May 30. Bioorg Med Chem Lett. 2016. PMID: 27287370

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