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11-trifluoromethyl-phenyldiazirinyl neurosteroid analogues: potent general anesthetics and photolabeling reagents for GABAA receptors.
Chen ZW, Wang C, Krishnan K, Manion BD, Hastings R, Bracamontes J, Taylor A, Eaton MM, Zorumski CF, Steinbach JH, Akk G, Mennerick S, Covey DF, Evers AS. Chen ZW, et al. Among authors: manion bd. Psychopharmacology (Berl). 2014 Sep;231(17):3479-91. doi: 10.1007/s00213-014-3568-4. Epub 2014 Apr 23. Psychopharmacology (Berl). 2014. PMID: 24756762 Free PMC article.
Neuroactive steroid interactions with voltage-dependent anion channels: lack of relationship to GABA(A) receptor modulation and anesthesia.
Darbandi-Tonkabon R, Manion BD, Hastings WR, Craigen WJ, Akk G, Bracamontes JR, He Y, Sheiko TV, Steinbach JH, Mennerick SJ, Covey DF, Evers AS. Darbandi-Tonkabon R, et al. Among authors: manion bd. J Pharmacol Exp Ther. 2004 Feb;308(2):502-11. doi: 10.1124/jpet.103.058123. Epub 2003 Oct 30. J Pharmacol Exp Ther. 2004. PMID: 14593090
Neurosteroid analogues. 9. Conformationally constrained pregnanes: structure-activity studies of 13,24-cyclo-18,21-dinorcholane analogues of the GABA modulatory and anesthetic steroids (3alpha,5alpha)- and (3alpha,5beta)-3-hydroxypregnan-20-one.
Jiang X, Manion BD, Benz A, Rath NP, Evers AS, Zorumski CF, Mennerick S, Covey DF. Jiang X, et al. Among authors: manion bd. J Med Chem. 2003 Dec 4;46(25):5334-48. doi: 10.1021/jm030302m. J Med Chem. 2003. PMID: 14640542
26 results