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The discovery of potent and selective non-steroidal glucocorticoid receptor modulators, suitable for inhalation.
Edman K, Ahlgren R, Bengtsson M, Bladh H, Bäckström S, Dahmén J, Henriksson K, Hillertz P, Hulikal V, Jerre A, Kinchin L, Kåse C, Lepistö M, Mile I, Nilsson S, Smailagic A, Taylor J, Tjörnebo A, Wissler L, Hansson T. Edman K, et al. Among authors: henriksson k. Bioorg Med Chem Lett. 2014 Jun 1;24(11):2571-7. doi: 10.1016/j.bmcl.2014.03.070. Epub 2014 Apr 2. Bioorg Med Chem Lett. 2014. PMID: 24755427
Selective Nonsteroidal Glucocorticoid Receptor Modulators for the Inhaled Treatment of Pulmonary Diseases.
Hemmerling M, Nilsson S, Edman K, Eirefelt S, Russell W, Hendrickx R, Johnsson E, Kärrman Mårdh C, Berger M, Rehwinkel H, Abrahamsson A, Dahmén J, Eriksson AR, Gabos B, Henriksson K, Hossain N, Ivanova S, Jansson AH, Jensen TJ, Jerre A, Johansson H, Klingstedt T, Lepistö M, Lindsjö M, Mile I, Nikitidis G, Steele J, Tehler U, Wissler L, Hansson T. Hemmerling M, et al. Among authors: henriksson k. J Med Chem. 2017 Oct 26;60(20):8591-8605. doi: 10.1021/acs.jmedchem.7b01215. Epub 2017 Oct 12. J Med Chem. 2017. PMID: 28937774
Topical 'dual-soft' glucocorticoid receptor agonist for dermatology.
Dack KN, Johnson PS, Henriksson K, Eirefelt S, Carnerup MA, Stahlhut M, Ollerstam AK. Dack KN, et al. Among authors: henriksson k. Bioorg Med Chem Lett. 2020 Sep 1;30(17):127402. doi: 10.1016/j.bmcl.2020.127402. Epub 2020 Jul 13. Bioorg Med Chem Lett. 2020. PMID: 32738970
221 results