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Improved HSC reconstitution and protection from inflammatory stress and chemotherapy in mice lacking granzyme B.
Carnevalli LS, Scognamiglio R, Cabezas-Wallscheid N, Rahmig S, Laurenti E, Masuda K, Jöckel L, Kuck A, Sujer S, Polykratis A, Erlacher M, Pasparakis M, Essers MA, Trumpp A. Carnevalli LS, et al. Among authors: pasparakis m. J Exp Med. 2014 May 5;211(5):769-79. doi: 10.1084/jem.20131072. Epub 2014 Apr 21. J Exp Med. 2014. PMID: 24752302 Free PMC article.
NEMO Prevents Steatohepatitis and Hepatocellular Carcinoma by Inhibiting RIPK1 Kinase Activity-Mediated Hepatocyte Apoptosis.
Kondylis V, Polykratis A, Ehlken H, Ochoa-Callejero L, Straub BK, Krishna-Subramanian S, Van TM, Curth HM, Heise N, Weih F, Klein U, Schirmacher P, Kelliher M, Pasparakis M. Kondylis V, et al. Among authors: pasparakis m. Cancer Cell. 2015 Nov 9;28(5):582-598. doi: 10.1016/j.ccell.2015.10.001. Cancer Cell. 2015. PMID: 26555174 Free PMC article.
RIPK1 and RIPK3 Kinases Promote Cell-Death-Independent Inflammation by Toll-like Receptor 4.
Najjar M, Saleh D, Zelic M, Nogusa S, Shah S, Tai A, Finger JN, Polykratis A, Gough PJ, Bertin J, Whalen M, Pasparakis M, Balachandran S, Kelliher M, Poltorak A, Degterev A. Najjar M, et al. Among authors: pasparakis m. Immunity. 2016 Jul 19;45(1):46-59. doi: 10.1016/j.immuni.2016.06.007. Epub 2016 Jul 5. Immunity. 2016. PMID: 27396959 Free PMC article.
202 results