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CSAHi study: Validation of multi-electrode array systems (MEA60/2100) for prediction of drug-induced proarrhythmia using human iPS cell-derived cardiomyocytes -assessment of inter-facility and cells lot-to-lot-variability.
Nozaki Y, Honda Y, Watanabe H, Saiki S, Koyabu K, Itoh T, Nagasawa C, Nakamori C, Nakayama C, Iwasaki H, Suzuki S, Washio I, Takahashi E, Miyamoto K, Yamanishi A, Endo H, Shinozaki J, Nogawa H, Kunimatsu T. Nozaki Y, et al. Among authors: kunimatsu t. Regul Toxicol Pharmacol. 2016 Jun;77:75-86. doi: 10.1016/j.yrtph.2016.02.007. Epub 2016 Feb 13. Regul Toxicol Pharmacol. 2016. PMID: 26884090
CSAHi study-2: Validation of multi-electrode array systems (MEA60/2100) for prediction of drug-induced proarrhythmia using human iPS cell-derived cardiomyocytes: Assessment of reference compounds and comparison with non-clinical studies and clinical information.
Nozaki Y, Honda Y, Watanabe H, Saiki S, Koyabu K, Itoh T, Nagasawa C, Nakamori C, Nakayama C, Iwasaki H, Suzuki S, Tanaka K, Takahashi E, Miyamoto K, Morimura K, Yamanishi A, Endo H, Shinozaki J, Nogawa H, Shinozawa T, Saito F, Kunimatsu T. Nozaki Y, et al. Among authors: kunimatsu t. Regul Toxicol Pharmacol. 2017 Aug;88:238-251. doi: 10.1016/j.yrtph.2017.06.006. Epub 2017 Jun 17. Regul Toxicol Pharmacol. 2017. PMID: 28634147
The effects of clobazam treatment in rats on the expression of genes and proteins encoding glucronosyltransferase 1A/2B (UGT1A/2B) and multidrug resistance-associated protein-2 (MRP2), and development of thyroid follicular cell hypertrophy.
Miyawaki I, Tamura A, Matsumoto I, Inada H, Kunimatsu T, Kimura J, Funabashi H. Miyawaki I, et al. Among authors: kunimatsu t. Toxicol Appl Pharmacol. 2012 Dec 15;265(3):351-9. doi: 10.1016/j.taap.2012.09.003. Epub 2012 Sep 12. Toxicol Appl Pharmacol. 2012. PMID: 22982618
53 results