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Structure of the aspartic protease plasmepsin 4 from the malarial parasite Plasmodium malariae bound to an allophenylnorstatine-based inhibitor.
Clemente JC, Govindasamy L, Madabushi A, Fisher SZ, Moose RE, Yowell CA, Hidaka K, Kimura T, Hayashi Y, Kiso Y, Agbandje-McKenna M, Dame JB, Dunn BM, McKenna R. Clemente JC, et al. Among authors: mckenna r. Acta Crystallogr D Biol Crystallogr. 2006 Mar;62(Pt 3):246-52. doi: 10.1107/S0907444905041260. Epub 2006 Feb 22. Acta Crystallogr D Biol Crystallogr. 2006. PMID: 16510971
Crystallization and preliminary X-ray analysis of the aspartic protease plasmepsin 4 from the malarial parasite Plasmodium malariae.
Madabushi A, Chakraborty S, Fisher SZ, Clemente JC, Yowell C, Agbandje-McKenna M, Dame JB, Dunn BM, McKenna R. Madabushi A, et al. Among authors: mckenna r. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005 Feb 1;61(Pt 2):228-31. doi: 10.1107/S1744309105001405. Epub 2005 Feb 1. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005. PMID: 16511002 Free PMC article.
Analysis of HIV-1 CRF_01 A/E protease inhibitor resistance: structural determinants for maintaining sensitivity and developing resistance to atazanavir.
Clemente JC, Coman RM, Thiaville MM, Janka LK, Jeung JA, Nukoolkarn S, Govindasamy L, Agbandje-McKenna M, McKenna R, Leelamanit W, Goodenow MM, Dunn BM. Clemente JC, et al. Among authors: mckenna r. Biochemistry. 2006 May 2;45(17):5468-77. doi: 10.1021/bi051886s. Biochemistry. 2006. PMID: 16634628 Free PMC article.
Design, synthesis, evaluation, and crystallographic-based structural studies of HIV-1 protease inhibitors with reduced response to the V82A mutation.
Clemente JC, Robbins A, Graña P, Paleo MR, Correa JF, Villaverde MC, Sardina FJ, Govindasamy L, Agbandje-McKenna M, McKenna R, Dunn BM, Sussman F. Clemente JC, et al. Among authors: mckenna r. J Med Chem. 2008 Feb 28;51(4):852-60. doi: 10.1021/jm701170f. Epub 2008 Jan 24. J Med Chem. 2008. PMID: 18215016
962 results