Izaurralde E - Search Results

1

Structural basis for the Nanos-mediated recruitment of the CCR4-NOT complex and translational repression.

Bhandari D, Raisch T, Weichenrieder O, Jonas S, Izaurralde E. Bhandari D, et al. Among authors: izaurralde e. Genes Dev. 2014 Apr 15;28(8):888-901. doi: 10.1101/gad.237289.113. Genes Dev. 2014. PMID: 24736845 Free PMC article.

2

SMG6 interacts with the exon junction complex via two conserved EJC-binding motifs (EBMs) required for nonsense-mediated mRNA decay.

Kashima I, Jonas S, Jayachandran U, Buchwald G, Conti E, Lupas AN, Izaurralde E. Kashima I, et al. Among authors: izaurralde e. Genes Dev. 2010 Nov 1;24(21):2440-50. doi: 10.1101/gad.604610. Epub 2010 Oct 7. Genes Dev. 2010. PMID: 20930030 Free PMC article.

3

The structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4-NOT deadenylase complex.

Petit AP, Wohlbold L, Bawankar P, Huntzinger E, Schmidt S, Izaurralde E, Weichenrieder O. Petit AP, et al. Among authors: izaurralde e. Nucleic Acids Res. 2012 Nov;40(21):11058-72. doi: 10.1093/nar/gks883. Epub 2012 Sep 12. Nucleic Acids Res. 2012. PMID: 22977175 Free PMC article.

4

An unusual arrangement of two 14-3-3-like domains in the SMG5-SMG7 heterodimer is required for efficient nonsense-mediated mRNA decay.

Jonas S, Weichenrieder O, Izaurralde E. Jonas S, et al. Among authors: izaurralde e. Genes Dev. 2013 Jan 15;27(2):211-25. doi: 10.1101/gad.206672.112. Genes Dev. 2013. PMID: 23348841 Free PMC article.

5

The SMG5-SMG7 heterodimer directly recruits the CCR4-NOT deadenylase complex to mRNAs containing nonsense codons via interaction with POP2.

Loh B, Jonas S, Izaurralde E. Loh B, et al. Among authors: izaurralde e. Genes Dev. 2013 Oct 1;27(19):2125-38. doi: 10.1101/gad.226951.113. Genes Dev. 2013. PMID: 24115769 Free PMC article.

6

Structure and assembly of the NOT module of the human CCR4-NOT complex.

Boland A, Chen Y, Raisch T, Jonas S, Kuzuoğlu-Öztürk D, Wohlbold L, Weichenrieder O, Izaurralde E. Boland A, et al. Among authors: izaurralde e. Nat Struct Mol Biol. 2013 Nov;20(11):1289-97. doi: 10.1038/nsmb.2681. Epub 2013 Oct 13. Nat Struct Mol Biol. 2013. PMID: 24121232

7

The role of disordered protein regions in the assembly of decapping complexes and RNP granules.

Jonas S, Izaurralde E. Jonas S, et al. Among authors: izaurralde e. Genes Dev. 2013 Dec 15;27(24):2628-41. doi: 10.1101/gad.227843.113. Genes Dev. 2013. PMID: 24352420 Free PMC article. Review.

8

Towards a molecular understanding of microRNA-mediated gene silencing.

Jonas S, Izaurralde E. Jonas S, et al. Among authors: izaurralde e. Nat Rev Genet. 2015 Jul;16(7):421-33. doi: 10.1038/nrg3965. Epub 2015 Jun 16. Nat Rev Genet. 2015. PMID: 26077373 Review.

9

Mextli proteins use both canonical bipartite and novel tripartite binding modes to form eIF4E complexes that display differential sensitivity to 4E-BP regulation.

Peter D, Weber R, Köne C, Chung MY, Ebertsch L, Truffault V, Weichenrieder O, Igreja C, Izaurralde E. Peter D, et al. Among authors: izaurralde e. Genes Dev. 2015 Sep 1;29(17):1835-49. doi: 10.1101/gad.269068.115. Epub 2015 Aug 20. Genes Dev. 2015. PMID: 26294658 Free PMC article.

10

Distinct modes of recruitment of the CCR4-NOT complex by Drosophila and vertebrate Nanos.

Raisch T, Bhandari D, Sabath K, Helms S, Valkov E, Weichenrieder O, Izaurralde E. Raisch T, et al. Among authors: izaurralde e. EMBO J. 2016 May 2;35(9):974-90. doi: 10.15252/embj.201593634. Epub 2016 Mar 11. EMBO J. 2016. PMID: 26968986 Free PMC article.

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