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Page 1
The discovery of potent nonstructural protein 5A (NS5A) inhibitors with a unique resistance profile-Part 1.
Tran TD, Wakenhut F, Pickford C, Shaw S, Westby M, Smith-Burchnell C, Watson L, Paradowski M, Milbank J, Brimage RA, Halstead R, Glen R, Wilson CP, Adam F, Hay D, Chiva JY, Nichols C, Blakemore DC, Gardner I, Dayal S, Pike A, Webster R, Pryde DC. Tran TD, et al. Among authors: blakemore dc. ChemMedChem. 2014 Jul;9(7):1378-86. doi: 10.1002/cmdc.201400045. Epub 2014 Apr 11. ChemMedChem. 2014. PMID: 24729513
The design and discovery of novel amide CCR5 antagonists.
Pryde DC, Corless M, Fenwick DR, Mason HJ, Stammen BC, Stephenson PT, Ellis D, Bachelor D, Gordon D, Barber CG, Wood A, Middleton DS, Blakemore DC, Parsons GC, Eastwood R, Platts MY, Statham K, Paradowski KA, Burt C, Klute W. Pryde DC, et al. Among authors: blakemore dc. Bioorg Med Chem Lett. 2009 Feb 15;19(4):1084-8. doi: 10.1016/j.bmcl.2009.01.012. Epub 2009 Jan 10. Bioorg Med Chem Lett. 2009. PMID: 19167884
Selection of a novel anti-nicotine vaccine: influence of antigen design on antibody function in mice.
Pryde DC, Jones LH, Gervais DP, Stead DR, Blakemore DC, Selby MD, Brown AD, Coe JW, Badland M, Beal DM, Glen R, Wharton Y, Miller GJ, White P, Zhang N, Benoit M, Robertson K, Merson JR, Davis HL, McCluskie MJ. Pryde DC, et al. Among authors: blakemore dc. PLoS One. 2013 Oct 1;8(10):e76557. doi: 10.1371/journal.pone.0076557. eCollection 2013. PLoS One. 2013. PMID: 24098532 Free PMC article.
The discovery of potent nonstructural protein 5A (NS5A) inhibitors with a unique resistance profile-Part 2.
Wakenhut F, Tran TD, Pickford C, Shaw S, Westby M, Smith-Burchnell C, Watson L, Paradowski M, Milbank J, Stonehouse D, Cheung K, Wybrow R, Daverio F, Crook S, Statham K, Leese D, Stead D, Adam F, Hay D, Roberts LR, Chiva JY, Nichols C, Blakemore DC, Goetz GH, Che Y, Gardner I, Dayal S, Pike A, Webster R, Pryde DC. Wakenhut F, et al. Among authors: blakemore dc. ChemMedChem. 2014 Jul;9(7):1387-96. doi: 10.1002/cmdc.201400046. Epub 2014 Apr 11. ChemMedChem. 2014. PMID: 24729518
Fluorine in drug design: a case study with fluoroanisoles.
Xing L, Blakemore DC, Narayanan A, Unwalla R, Lovering F, Denny RA, Zhou H, Bunnage ME. Xing L, et al. Among authors: blakemore dc. ChemMedChem. 2015 Apr;10(4):715-26. doi: 10.1002/cmdc.201402555. Epub 2015 Mar 6. ChemMedChem. 2015. PMID: 25755132
Highly potent and selective NaV1.7 inhibitors for use as intravenous agents and chemical probes.
Storer RI, Pike A, Swain NA, Alexandrou AJ, Bechle BM, Blakemore DC, Brown AD, Castle NA, Corbett MS, Flanagan NJ, Fengas D, Johnson MS, Jones LH, Marron BE, Payne CE, Printzenhoff D, Rawson DJ, Rose CR, Ryckmans T, Sun J, Theile JW, Torella R, Tseng E, Warmus JS. Storer RI, et al. Among authors: blakemore dc. Bioorg Med Chem Lett. 2017 Nov 1;27(21):4805-4811. doi: 10.1016/j.bmcl.2017.09.056. Epub 2017 Sep 28. Bioorg Med Chem Lett. 2017. PMID: 29029933
65 results