Hayashi Y - Search Results

1

Effect of ketoconazole on the pharmacokinetics of the dipeptidyl peptidase-4 inhibitor teneligliptin: an open-label study in healthy white subjects in Germany.

Nakamaru Y, Hayashi Y, Sekine M, Kinoshita S, Thompson J, Kawaguchi A, Davies M, Jürgen Heuer H, Yamazaki H, Akimoto K. Nakamaru Y, et al. Among authors: hayashi y. Clin Ther. 2014 May;36(5):760-9. doi: 10.1016/j.clinthera.2014.03.002. Epub 2014 Apr 13. Clin Ther. 2014. PMID: 24726088 Clinical Trial.

2

Metabolism and disposition of the dipeptidyl peptidase IV inhibitor teneligliptin in humans.

Nakamaru Y, Hayashi Y, Ikegawa R, Kinoshita S, Perez Madera B, Gunput D, Kawaguchi A, Davies M, Mair S, Yamazaki H, Kume T, Suzuki M. Nakamaru Y, et al. Among authors: hayashi y. Xenobiotica. 2014 Mar;44(3):242-53. doi: 10.3109/00498254.2013.816891. Epub 2013 Jul 15. Xenobiotica. 2014. PMID: 23855261 Clinical Trial.

3

Investigation of Potential Pharmacokinetic Interactions Between Teneligliptin and Metformin in Steady-state Conditions in Healthy Adults.

Nakamaru Y, Hayashi Y, Davies M, Jürgen Heuer H, Hisanaga N, Akimoto K. Nakamaru Y, et al. Among authors: hayashi y. Clin Ther. 2015 Sep;37(9):2007-18. doi: 10.1016/j.clinthera.2015.06.012. Epub 2015 Jul 23. Clin Ther. 2015. PMID: 26212570 Clinical Trial.

4

Discovery and preclinical profile of teneligliptin (3-[(2S,4S)-4-[4-(3-methyl-1-phenyl-1H-pyrazol-5-yl)piperazin-1-yl]pyrrolidin-2-ylcarbonyl]thiazolidine): a highly potent, selective, long-lasting and orally active dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes.

Yoshida T, Akahoshi F, Sakashita H, Kitajima H, Nakamura M, Sonda S, Takeuchi M, Tanaka Y, Ueda N, Sekiguchi S, Ishige T, Shima K, Nabeno M, Abe Y, Anabuki J, Soejima A, Yoshida K, Takashina Y, Ishii S, Kiuchi S, Fukuda S, Tsutsumiuchi R, Kosaka K, Murozono T, Nakamaru Y, Utsumi H, Masutomi N, Kishida H, Miyaguchi I, Hayashi Y. Yoshida T, et al. Among authors: hayashi y. Bioorg Med Chem. 2012 Oct 1;20(19):5705-19. doi: 10.1016/j.bmc.2012.08.012. Epub 2012 Aug 17. Bioorg Med Chem. 2012. PMID: 22959556

5

Slow R-warfarin 7-hydroxylation mediated by P450 2C19 genetic variants in cynomolgus monkeys in vivo.

Utoh M, Yoshikawa T, Hayashi Y, Shimizu M, Iwasaki K, Uno Y, Yamazaki H. Utoh M, et al. Among authors: hayashi y. Biochem Pharmacol. 2015 May 15;95(2):110-4. doi: 10.1016/j.bcp.2015.03.008. Epub 2015 Mar 20. Biochem Pharmacol. 2015. PMID: 25801008

6

[Pharmacological and clinical profile of a novel DPP-4 inhibitor teneligliptin hydrobromide hydrate (TENELIA(®)].

Goda M, Akahoshi F, Ishii S, Terata R, Hayashi Y. Goda M, et al. Among authors: hayashi y. Nihon Yakurigaku Zasshi. 2013 Sep;142(3):134-43. doi: 10.1254/fpj.142.134. Nihon Yakurigaku Zasshi. 2013. PMID: 24025495 Review. Japanese. No abstract available.

7

Fused bicyclic heteroarylpiperazine-substituted L-prolylthiazolidines as highly potent DPP-4 inhibitors lacking the electrophilic nitrile group.

Yoshida T, Akahoshi F, Sakashita H, Sonda S, Takeuchi M, Tanaka Y, Nabeno M, Kishida H, Miyaguchi I, Hayashi Y. Yoshida T, et al. Among authors: hayashi y. Bioorg Med Chem. 2012 Aug 15;20(16):5033-41. doi: 10.1016/j.bmc.2012.06.033. Epub 2012 Jul 5. Bioorg Med Chem. 2012. PMID: 22824762

8

1-((S)-gamma-substituted prolyl)-(S)-2-cyanopyrrolidine as a novel series of highly potent DPP-IV inhibitors.

Sakashita H, Kitajima H, Nakamura M, Akahoshi F, Hayashi Y. Sakashita H, et al. Among authors: hayashi y. Bioorg Med Chem Lett. 2005 May 16;15(10):2441-5. doi: 10.1016/j.bmcl.2005.03.077. Bioorg Med Chem Lett. 2005. PMID: 15863294

9

[(S)-gamma-(Arylamino)prolyl]thiazolidine compounds as a novel series of potent and stable DPP-IV inhibitors.

Sakashita H, Akahoshi F, Kitajima H, Tsutsumiuchi R, Hayashi Y. Sakashita H, et al. Among authors: hayashi y. Bioorg Med Chem. 2006 Jun 1;14(11):3662-71. doi: 10.1016/j.bmc.2006.01.022. Epub 2006 Feb 7. Bioorg Med Chem. 2006. PMID: 16460948

10

[(S)-gamma-(4-Aryl-1-piperazinyl)-l-prolyl]thiazolidines as a novel series of highly potent and long-lasting DPP-IV inhibitors.

Yoshida T, Sakashita H, Akahoshi F, Hayashi Y. Yoshida T, et al. Among authors: hayashi y. Bioorg Med Chem Lett. 2007 May 1;17(9):2618-21. doi: 10.1016/j.bmcl.2007.01.110. Epub 2007 Feb 8. Bioorg Med Chem Lett. 2007. PMID: 17317162

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

8,258 results

Search Page

Filters