Xiong Y - Search Results

1

Ribosomal protein s15 phosphorylation mediates LRRK2 neurodegeneration in Parkinson's disease.

Martin I, Kim JW, Lee BD, Kang HC, Xu JC, Jia H, Stankowski J, Kim MS, Zhong J, Kumar M, Andrabi SA, Xiong Y, Dickson DW, Wszolek ZK, Pandey A, Dawson TM, Dawson VL. Martin I, et al. Among authors: xiong y. Cell. 2014 Apr 10;157(2):472-485. doi: 10.1016/j.cell.2014.01.064. Cell. 2014. PMID: 24725412 Free PMC article.

2

GTPase activity plays a key role in the pathobiology of LRRK2.

Xiong Y, Coombes CE, Kilaru A, Li X, Gitler AD, Bowers WJ, Dawson VL, Dawson TM, Moore DJ. Xiong Y, et al. PLoS Genet. 2010 Apr 8;6(4):e1000902. doi: 10.1371/journal.pgen.1000902. PLoS Genet. 2010. PMID: 20386743 Free PMC article.

3

Reevaluation of phosphorylation sites in the Parkinson disease-associated leucine-rich repeat kinase 2.

Li X, Moore DJ, Xiong Y, Dawson TM, Dawson VL. Li X, et al. Among authors: xiong y. J Biol Chem. 2010 Sep 17;285(38):29569-76. doi: 10.1074/jbc.M110.127639. Epub 2010 Jul 1. J Biol Chem. 2010. PMID: 20595391 Free PMC article.

4

The AAA+ ATPase Thorase regulates AMPA receptor-dependent synaptic plasticity and behavior.

Zhang J, Wang Y, Chi Z, Keuss MJ, Pai YM, Kang HC, Shin JH, Bugayenko A, Wang H, Xiong Y, Pletnikov MV, Mattson MP, Dawson TM, Dawson VL. Zhang J, et al. Among authors: xiong y. Cell. 2011 Apr 15;145(2):284-99. doi: 10.1016/j.cell.2011.03.016. Cell. 2011. PMID: 21496646 Free PMC article.

5

Transcriptional responses to loss or gain of function of the leucine-rich repeat kinase 2 (LRRK2) gene uncover biological processes modulated by LRRK2 activity.

Nikonova EV, Xiong Y, Tanis KQ, Dawson VL, Vogel RL, Finney EM, Stone DJ, Reynolds IJ, Kern JT, Dawson TM. Nikonova EV, et al. Among authors: xiong y. Hum Mol Genet. 2012 Jan 1;21(1):163-74. doi: 10.1093/hmg/ddr451. Epub 2011 Oct 4. Hum Mol Genet. 2012. PMID: 21972245 Free PMC article.

6

ArfGAP1 is a GTPase activating protein for LRRK2: reciprocal regulation of ArfGAP1 by LRRK2.

Xiong Y, Yuan C, Chen R, Dawson TM, Dawson VL. Xiong Y, et al. J Neurosci. 2012 Mar 14;32(11):3877-86. doi: 10.1523/JNEUROSCI.4566-11.2012. J Neurosci. 2012. PMID: 22423108 Free PMC article.

7

LRRK2 GTPase dysfunction in the pathogenesis of Parkinson's disease.

Xiong Y, Dawson VL, Dawson TM. Xiong Y, et al. Biochem Soc Trans. 2012 Oct;40(5):1074-9. doi: 10.1042/BST20120093. Biochem Soc Trans. 2012. PMID: 22988868 Free PMC article. Review.

8

LRRK2 affects vesicle trafficking, neurotransmitter extracellular level and membrane receptor localization.

Migheli R, Del Giudice MG, Spissu Y, Sanna G, Xiong Y, Dawson TM, Dawson VL, Galioto M, Rocchitta G, Biosa A, Serra PA, Carri MT, Crosio C, Iaccarino C. Migheli R, et al. Among authors: xiong y. PLoS One. 2013 Oct 22;8(10):e77198. doi: 10.1371/journal.pone.0077198. eCollection 2013. PLoS One. 2013. PMID: 24167564 Free PMC article.

9

Functional interaction of Parkinson's disease-associated LRRK2 with members of the dynamin GTPase superfamily.

Stafa K, Tsika E, Moser R, Musso A, Glauser L, Jones A, Biskup S, Xiong Y, Bandopadhyay R, Dawson VL, Dawson TM, Moore DJ. Stafa K, et al. Among authors: xiong y. Hum Mol Genet. 2014 Apr 15;23(8):2055-77. doi: 10.1093/hmg/ddt600. Epub 2013 Nov 26. Hum Mol Genet. 2014. PMID: 24282027 Free PMC article.

10

LRRK2 G2019S transgenic mice display increased susceptibility to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-mediated neurotoxicity.

Karuppagounder SS, Xiong Y, Lee Y, Lawless MC, Kim D, Nordquist E, Martin I, Ge P, Brahmachari S, Jhaldiyal A, Kumar M, Andrabi SA, Dawson TM, Dawson VL. Karuppagounder SS, et al. Among authors: xiong y. J Chem Neuroanat. 2016 Oct;76(Pt B):90-97. doi: 10.1016/j.jchemneu.2016.01.007. Epub 2016 Jan 22. J Chem Neuroanat. 2016. PMID: 26808467 Free PMC article.

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