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Page 1
Copper is required for oncogenic BRAF signalling and tumorigenesis.
Brady DC, Crowe MS, Turski ML, Hobbs GA, Yao X, Chaikuad A, Knapp S, Xiao K, Campbell SL, Thiele DJ, Counter CM. Brady DC, et al. Among authors: hobbs ga. Nature. 2014 May 22;509(7501):492-6. doi: 10.1038/nature13180. Epub 2014 Apr 9. Nature. 2014. PMID: 24717435 Free PMC article.
Redox regulation of Ras and Rho GTPases: mechanism and function.
Mitchell L, Hobbs GA, Aghajanian A, Campbell SL. Mitchell L, et al. Among authors: hobbs ga. Antioxid Redox Signal. 2013 Jan 20;18(3):250-8. doi: 10.1089/ars.2012.4687. Epub 2012 Jul 30. Antioxid Redox Signal. 2013. PMID: 22657737 Free PMC article. Review.
Rho GTPases, oxidation, and cell redox control.
Hobbs GA, Zhou B, Cox AD, Campbell SL. Hobbs GA, et al. Small GTPases. 2014;5:e28579. doi: 10.4161/sgtp.28579. Epub 2014 May 8. Small GTPases. 2014. PMID: 24809833 Free PMC article. Review.
Redox regulation of Rac1 by thiol oxidation.
Hobbs GA, Mitchell LE, Arrington ME, Gunawardena HP, DeCristo MJ, Loeser RF, Chen X, Cox AD, Campbell SL. Hobbs GA, et al. Free Radic Biol Med. 2015 Feb;79:237-50. doi: 10.1016/j.freeradbiomed.2014.09.027. Epub 2014 Oct 5. Free Radic Biol Med. 2015. PMID: 25289457 Free PMC article.
Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer.
Bryant KL, Stalnecker CA, Zeitouni D, Klomp JE, Peng S, Tikunov AP, Gunda V, Pierobon M, Waters AM, George SD, Tomar G, Papke B, Hobbs GA, Yan L, Hayes TK, Diehl JN, Goode GD, Chaika NV, Wang Y, Zhang GF, Witkiewicz AK, Knudsen ES, Petricoin EF 3rd, Singh PK, Macdonald JM, Tran NL, Lyssiotis CA, Ying H, Kimmelman AC, Cox AD, Der CJ. Bryant KL, et al. Among authors: hobbs ga. Nat Med. 2019 Apr;25(4):628-640. doi: 10.1038/s41591-019-0368-8. Epub 2019 Mar 4. Nat Med. 2019. PMID: 30833752 Free PMC article.
Atypical KRASG12R Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer.
Hobbs GA, Baker NM, Miermont AM, Thurman RD, Pierobon M, Tran TH, Anderson AO, Waters AM, Diehl JN, Papke B, Hodge RG, Klomp JE, Goodwin CM, DeLiberty JM, Wang J, Ng RWS, Gautam P, Bryant KL, Esposito D, Campbell SL, Petricoin EF 3rd, Simanshu DK, Aguirre AJ, Wolpin BM, Wennerberg K, Rudloff U, Cox AD, Der CJ. Hobbs GA, et al. Cancer Discov. 2020 Jan;10(1):104-123. doi: 10.1158/2159-8290.CD-19-1006. Epub 2019 Oct 24. Cancer Discov. 2020. PMID: 31649109 Free PMC article.
Oncogenic KRAS G12C: Kinetic and redox characterization of covalent inhibition.
Huynh MV, Parsonage D, Forshaw TE, Chirasani VR, Hobbs GA, Wu H, Lee J, Furdui CM, Poole LB, Campbell SL. Huynh MV, et al. Among authors: hobbs ga. J Biol Chem. 2022 Aug;298(8):102186. doi: 10.1016/j.jbc.2022.102186. Epub 2022 Jun 24. J Biol Chem. 2022. PMID: 35753348 Free PMC article.
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