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Palladacycle (BPC) antitumour activity against resistant and metastatic cell lines: the relationship with cytosolic calcium mobilisation and cathepsin B activity.
Bechara A, Barbosa CM, Paredes-Gamero EJ, Garcia DM, Silva LS, Matsuo AL, Nascimento FD, Rodrigues EG, Caires AC, Smaili SS, Bincoletto C. Bechara A, et al. Among authors: rodrigues eg. Eur J Med Chem. 2014 May 22;79:24-33. doi: 10.1016/j.ejmech.2014.03.073. Epub 2014 Mar 28. Eur J Med Chem. 2014. PMID: 24709226
A cyclopalladated complex interacts with mitochondrial membrane thiol-groups and induces the apoptotic intrinsic pathway in murine and cisplatin-resistant human tumor cells.
Serrano FA, Matsuo AL, Monteforte PT, Bechara A, Smaili SS, Santana DP, Rodrigues T, Pereira FV, Silva LS, Machado J Jr, Santos EL, Pesquero JB, Martins RM, Travassos LR, Caires AC, Rodrigues EG. Serrano FA, et al. Among authors: rodrigues t, rodrigues eg. BMC Cancer. 2011 Jul 14;11:296. doi: 10.1186/1471-2407-11-296. BMC Cancer. 2011. PMID: 21756336 Free PMC article.
C7a, a biphosphinic cyclopalladated compound, efficiently controls the development of a patient-derived xenograft model of adult T cell leukemia/lymphoma.
Guimaraes-Correa AB, Crawford LB, Figueiredo CR, Gimenes KP, Pinto LA, Grassi MFR, Feuer G, Travassos LR, Caires ACF, Rodrigues EG, Marriott SJ. Guimaraes-Correa AB, et al. Among authors: rodrigues eg. Viruses. 2011 Jul;3(7):1041-1058. doi: 10.3390/v3071041. Epub 2011 Jul 5. Viruses. 2011. PMID: 21994769 Free PMC article.
β-Actin-binding complementarity-determining region 2 of variable heavy chain from monoclonal antibody C7 induces apoptosis in several human tumor cells and is protective against metastatic melanoma.
Arruda DC, Santos LC, Melo FM, Pereira FV, Figueiredo CR, Matsuo AL, Mortara RA, Juliano MA, Rodrigues EG, Dobroff AS, Polonelli L, Travassos LR. Arruda DC, et al. Among authors: rodrigues eg. J Biol Chem. 2012 Apr 27;287(18):14912-22. doi: 10.1074/jbc.M111.322362. Epub 2012 Feb 13. J Biol Chem. 2012. PMID: 22334655 Free PMC article.
95 results