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Lysine glutarylation is a protein posttranslational modification regulated by SIRT5.
Tan M, Peng C, Anderson KA, Chhoy P, Xie Z, Dai L, Park J, Chen Y, Huang H, Zhang Y, Ro J, Wagner GR, Green MF, Madsen AS, Schmiesing J, Peterson BS, Xu G, Ilkayeva OR, Muehlbauer MJ, Braulke T, Mühlhausen C, Backos DS, Olsen CA, McGuire PJ, Pletcher SD, Lombard DB, Hirschey MD, Zhao Y. Tan M, et al. Among authors: pletcher sd. Cell Metab. 2014 Apr 1;19(4):605-17. doi: 10.1016/j.cmet.2014.03.014. Cell Metab. 2014. PMID: 24703693 Free PMC article.
Ageing: longevity hits a roadblock.
Lombard DB, Pletcher SD, Cantó C, Auwerx J. Lombard DB, et al. Among authors: pletcher sd. Nature. 2011 Sep 21;477(7365):410-1. doi: 10.1038/477410a. Nature. 2011. PMID: 21938058 No abstract available.
Measurement of lifespan in Drosophila melanogaster.
Linford NJ, Bilgir C, Ro J, Pletcher SD. Linford NJ, et al. Among authors: pletcher sd. J Vis Exp. 2013 Jan 7;(71):50068. doi: 10.3791/50068. J Vis Exp. 2013. PMID: 23328955 Free PMC article.
Gustatory and metabolic perception of nutrient stress in Drosophila.
Linford NJ, Ro J, Chung BY, Pletcher SD. Linford NJ, et al. Among authors: pletcher sd. Proc Natl Acad Sci U S A. 2015 Feb 24;112(8):2587-92. doi: 10.1073/pnas.1401501112. Epub 2015 Feb 9. Proc Natl Acad Sci U S A. 2015. PMID: 25675472 Free PMC article.
Metabolic Regulation of Gene Expression by Histone Lysine β-Hydroxybutyrylation.
Xie Z, Zhang D, Chung D, Tang Z, Huang H, Dai L, Qi S, Li J, Colak G, Chen Y, Xia C, Peng C, Ruan H, Kirkey M, Wang D, Jensen LM, Kwon OK, Lee S, Pletcher SD, Tan M, Lombard DB, White KP, Zhao H, Li J, Roeder RG, Yang X, Zhao Y. Xie Z, et al. Among authors: pletcher sd. Mol Cell. 2016 Apr 21;62(2):194-206. doi: 10.1016/j.molcel.2016.03.036. Mol Cell. 2016. PMID: 27105115 Free PMC article.
Serotonin signaling mediates protein valuation and aging.
Ro J, Pak G, Malec PA, Lyu Y, Allison DB, Kennedy RT, Pletcher SD. Ro J, et al. Among authors: pletcher sd. Elife. 2016 Aug 23;5:e16843. doi: 10.7554/eLife.16843. Elife. 2016. PMID: 27572262 Free PMC article.
High-throughput small molecule screening reveals Nrf2-dependent and -independent pathways of cellular stress resistance.
Lombard DB, Kohler WJ, Guo AH, Gendron C, Han M, Ding W, Lyu Y, Ching TT, Wang FY, Chakraborty TS, Nikolovska-Coleska Z, Duan Y, Girke T, Hsu AL, Pletcher SD, Miller RA. Lombard DB, et al. Among authors: pletcher sd. Sci Adv. 2020 Oct 2;6(40):eaaz7628. doi: 10.1126/sciadv.aaz7628. Print 2020 Oct. Sci Adv. 2020. PMID: 33008901 Free PMC article.
172 results