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Linker length matters, fynomer-Fc fusion with an optimized linker displaying picomolar IL-17A inhibition potency.
J Biol Chem. 2014 May 16;289(20):14392-8. doi: 10.1074/jbc.M113.534578. Epub 2014 Apr 1.
J Biol Chem. 2014.
PMID: 24692552
Free PMC article.
Discovery and characterization of COVA322, a clinical-stage bispecific TNF/IL-17A inhibitor for the treatment of inflammatory diseases.
Silacci M, Lembke W, Woods R, Attinger-Toller I, Baenziger-Tobler N, Batey S, Santimaria R, von der Bey U, Koenig-Friedrich S, Zha W, Schlereth B, Locher M, Bertschinger J, Grabulovski D.
Silacci M, et al. Among authors: baenziger tobler n.
MAbs. 2016;8(1):141-9. doi: 10.1080/19420862.2015.1093266. Epub 2015 Sep 22.
MAbs. 2016.
PMID: 26390837
Free PMC article.
Clinical Trial.
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Activation of the epidermal growth factor receptor promotes lymphangiogenesis in the skin.
Marino D, Angehrn Y, Klein S, Riccardi S, Baenziger-Tobler N, Otto VI, Pittelkow M, Detmar M.
Marino D, et al. Among authors: baenziger tobler n.
J Dermatol Sci. 2013 Sep;71(3):184-94. doi: 10.1016/j.jdermsci.2013.04.024. Epub 2013 May 4.
J Dermatol Sci. 2013.
PMID: 23706492
Free PMC article.
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