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Page 1
Phenobarbital induces cell cycle transcriptional responses in mouse liver humanized for constitutive androstane and pregnane x receptors.
Luisier R, Lempiäinen H, Scherbichler N, Braeuning A, Geissler M, Dubost V, Müller A, Scheer N, Chibout SD, Hara H, Picard F, Theil D, Couttet P, Vitobello A, Grenet O, Grasl-Kraupp B, Ellinger-Ziegelbauer H, Thomson JP, Meehan RR, Elcombe CR, Henderson CJ, Wolf CR, Schwarz M, Moulin P, Terranova R, Moggs JG. Luisier R, et al. Among authors: wolf cr. Toxicol Sci. 2014 Jun;139(2):501-11. doi: 10.1093/toxsci/kfu038. Epub 2014 Apr 1. Toxicol Sci. 2014. PMID: 24690595
Human constitutive androstane receptor (CAR) and pregnane X receptor (PXR) support the hypertrophic but not the hyperplastic response to the murine nongenotoxic hepatocarcinogens phenobarbital and chlordane in vivo.
Ross J, Plummer SM, Rode A, Scheer N, Bower CC, Vogel O, Henderson CJ, Wolf CR, Elcombe CR. Ross J, et al. Among authors: wolf cr. Toxicol Sci. 2010 Aug;116(2):452-66. doi: 10.1093/toxsci/kfq118. Epub 2010 Apr 19. Toxicol Sci. 2010. PMID: 20403969
Loss of Tet1-Associated 5-Hydroxymethylcytosine Is Concomitant with Aberrant Promoter Hypermethylation in Liver Cancer.
Thomson JP, Ottaviano R, Unterberger EB, Lempiäinen H, Muller A, Terranova R, Illingworth RS, Webb S, Kerr AR, Lyall MJ, Drake AJ, Wolf CR, Moggs JG, Schwarz M, Meehan RR. Thomson JP, et al. Among authors: wolf cr. Cancer Res. 2016 May 15;76(10):3097-108. doi: 10.1158/0008-5472.CAN-15-1910. Epub 2016 Apr 6. Cancer Res. 2016. PMID: 27197233 Free PMC article.
Drug-induced chromatin accessibility changes associate with sensitivity to liver tumor promotion.
Vitobello A, Perner J, Beil J, Zhu J, Del Río-Espínola A, Morawiec L, Westphal M, Dubost V, Altorfer M, Naumann U, Mueller A, Kapur K, Borowsky M, Henderson C, Wolf CR, Schwarz M, Moggs J, Terranova R. Vitobello A, et al. Among authors: wolf cr. Life Sci Alliance. 2019 Oct 15;2(5):e201900461. doi: 10.26508/lsa.201900461. Print 2019 Oct. Life Sci Alliance. 2019. PMID: 31615920 Free PMC article.
Epigenetic profiles as defined signatures of xenobiotic exposure.
Thomson JP, Moggs JG, Wolf CR, Meehan RR. Thomson JP, et al. Among authors: wolf cr. Mutat Res Genet Toxicol Environ Mutagen. 2014 Apr;764-765:3-9. doi: 10.1016/j.mrgentox.2013.08.007. Epub 2013 Aug 31. Mutat Res Genet Toxicol Environ Mutagen. 2014. PMID: 24001620 Review.
520 results