Sweasy JB - Search Results

1

The S229L colon tumor-associated variant of DNA polymerase β induces cellular transformation as a result of decreased polymerization efficiency.

Nemec AA, Murphy DL, Donigan KA, Sweasy JB. Nemec AA, et al. Among authors: sweasy jb. J Biol Chem. 2014 May 16;289(20):13708-16. doi: 10.1074/jbc.M114.550400. Epub 2014 Mar 25. J Biol Chem. 2014. PMID: 24668809 Free PMC article.

2

DNA polymerase beta can substitute for DNA polymerase I in the initiation of plasmid DNA replication.

Sweasy JB, Chen M, Loeb LA. Sweasy JB, et al. J Bacteriol. 1995 May;177(10):2923-5. doi: 10.1128/jb.177.10.2923-2925.1995. J Bacteriol. 1995. PMID: 7751308 Free PMC article.

3

Increased activity and fidelity of DNA polymerase beta on single-nucleotide gapped DNA.

Chagovetz AM, Sweasy JB, Preston BD. Chagovetz AM, et al. Among authors: sweasy jb. J Biol Chem. 1997 Oct 31;272(44):27501-4. doi: 10.1074/jbc.272.44.27501. J Biol Chem. 1997. PMID: 9346877 Free article.

4

3'-Azido-3'-deoxythymidine-resistant mutants of DNA polymerase beta identified by in vivo selection.

Kosa JL, Sweasy JB. Kosa JL, et al. Among authors: sweasy jb. J Biol Chem. 1999 Feb 5;274(6):3851-8. doi: 10.1074/jbc.274.6.3851. J Biol Chem. 1999. PMID: 9920940 Free article.

5

The E249K mutator mutant of DNA polymerase beta extends mispaired termini.

Kosa JL, Sweasy JB. Kosa JL, et al. Among authors: sweasy jb. J Biol Chem. 1999 Dec 10;274(50):35866-72. doi: 10.1074/jbc.274.50.35866. J Biol Chem. 1999. PMID: 10585471 Free article.

6

Y265H mutator mutant of DNA polymerase beta. Proper teometric alignment is critical for fidelity.

Shah AM, Li SX, Anderson KS, Sweasy JB. Shah AM, et al. Among authors: sweasy jb. J Biol Chem. 2001 Apr 6;276(14):10824-31. doi: 10.1074/jbc.M008680200. Epub 2001 Jan 11. J Biol Chem. 2001. PMID: 11154692 Free article.

7

Threonine 79 is a hinge residue that governs the fidelity of DNA polymerase beta by helping to position the DNA within the active site.

Maitra M, Gudzelak A Jr, Li SX, Matsumoto Y, Eckert KA, Jager J, Sweasy JB. Maitra M, et al. Among authors: sweasy jb. J Biol Chem. 2002 Sep 20;277(38):35550-60. doi: 10.1074/jbc.M204953200. Epub 2002 Jul 16. J Biol Chem. 2002. PMID: 12121998 Free article.

8

Fidelity mechanisms of DNA polymerase beta.

Sweasy JB. Sweasy JB. Prog Nucleic Acid Res Mol Biol. 2003;73:137-69. doi: 10.1016/s0079-6603(03)01005-5. Prog Nucleic Acid Res Mol Biol. 2003. PMID: 12882517 Review.

9

The D246V mutant of DNA polymerase beta misincorporates nucleotides: evidence for a role for the flexible loop in DNA positioning within the active site.

Dalal S, Kosa JL, Sweasy JB. Dalal S, et al. Among authors: sweasy jb. J Biol Chem. 2004 Jan 2;279(1):577-84. doi: 10.1074/jbc.M309607200. Epub 2003 Oct 16. J Biol Chem. 2004. PMID: 14563842 Free article.

10

A DNA polymerase beta mutant from colon cancer cells induces mutations.

Lang T, Maitra M, Starcevic D, Li SX, Sweasy JB. Lang T, et al. Among authors: sweasy jb. Proc Natl Acad Sci U S A. 2004 Apr 20;101(16):6074-9. doi: 10.1073/pnas.0308571101. Epub 2004 Apr 9. Proc Natl Acad Sci U S A. 2004. PMID: 15075389 Free PMC article.

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