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Novel Furin Inhibitors with Potent Anti-infectious Activity.
Hardes K, Becker GL, Lu Y, Dahms SO, Köhler S, Beyer W, Sandvig K, Yamamoto H, Lindberg I, Walz L, von Messling V, Than ME, Garten W, Steinmetzer T. Hardes K, et al. ChemMedChem. 2015 Jul;10(7):1218-31. doi: 10.1002/cmdc.201500103. Epub 2015 May 14. ChemMedChem. 2015. PMID: 25974265
Peptidomimetic furin inhibitor MI-701 in combination with oseltamivir and ribavirin efficiently blocks propagation of highly pathogenic avian influenza viruses and delays high level oseltamivir resistance in MDCK cells.
Lu Y, Hardes K, Dahms SO, Böttcher-Friebertshäuser E, Steinmetzer T, Than ME, Klenk HD, Garten W. Lu Y, et al. Among authors: hardes k. Antiviral Res. 2015 Aug;120:89-100. doi: 10.1016/j.antiviral.2015.05.006. Epub 2015 May 26. Antiviral Res. 2015. PMID: 26022200
47 results