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A multi-objective optimization approach accurately resolves protein domain architectures.
Bernardes JS, Vieira FR, Zaverucha G, Carbone A. Bernardes JS, et al. Among authors: carbone a. Bioinformatics. 2016 Feb 1;32(3):345-53. doi: 10.1093/bioinformatics/btv582. Epub 2015 Oct 12. Bioinformatics. 2016. PMID: 26458889 Free PMC article.
MOTIVATION: Given a protein sequence and a number of potential domains matching it, what are the domain content and the most likely domain architecture for the sequence? ...RESULTS: We developed DAMA (Domain Annotation by a Multi-objective Approach), a
MOTIVATION: Given a protein sequence and a number of potential domains matching it, what are the domain content and the most l …
Reconstruction of ancestral chromosome architecture and gene repertoire reveals principles of genome evolution in a model yeast genus.
Vakirlis N, Sarilar V, Drillon G, Fleiss A, Agier N, Meyniel JP, Blanpain L, Carbone A, Devillers H, Dubois K, Gillet-Markowska A, Graziani S, Huu-Vang N, Poirel M, Reisser C, Schott J, Schacherer J, Lafontaine I, Llorente B, Neuvéglise C, Fischer G. Vakirlis N, et al. Among authors: carbone a. Genome Res. 2016 Jul;26(7):918-32. doi: 10.1101/gr.204420.116. Epub 2016 May 31. Genome Res. 2016. PMID: 27247244 Free PMC article.
Protein-protein interaction specificity is captured by contact preferences and interface composition.
Nadalin F, Carbone A. Nadalin F, et al. Among authors: carbone a. Bioinformatics. 2018 Feb 1;34(3):459-468. doi: 10.1093/bioinformatics/btx584. Bioinformatics. 2018. PMID: 29028884 Free PMC article.
Complete cross-docking experiments make in silico reconstruction of protein-protein interaction networks a feasible goal. They ask for efficient and accurate screening of the millions structural conformations issued by the calculations. RESULTS: We propose CIPS (Combined I …
Complete cross-docking experiments make in silico reconstruction of protein-protein interaction networks a feasible goal. They ask fo …
1,936 results