Yun MK - Search Results

1

Identification and characterization of an allosteric inhibitory site on dihydropteroate synthase.

Hammoudeh DI, Daté M, Yun MK, Zhang W, Boyd VA, Viacava Follis A, Griffith E, Lee RE, Bashford D, White SW. Hammoudeh DI, et al. Among authors: yun mk. ACS Chem Biol. 2014 Jun 20;9(6):1294-302. doi: 10.1021/cb500038g. Epub 2014 Mar 27. ACS Chem Biol. 2014. PMID: 24650357 Free PMC article.

2

Prokaryotic type II and type III pantothenate kinases: The same monomer fold creates dimers with distinct catalytic properties.

Hong BS, Yun MK, Zhang YM, Chohnan S, Rock CO, White SW, Jackowski S, Park HW, Leonardi R. Hong BS, et al. Among authors: yun mk. Structure. 2006 Aug;14(8):1251-61. doi: 10.1016/j.str.2006.06.008. Structure. 2006. PMID: 16905099 Free article.

3

Crystal structure and allosteric regulation of the cytoplasmic Escherichia coli L-asparaginase I.

Yun MK, Nourse A, White SW, Rock CO, Heath RJ. Yun MK, et al. J Mol Biol. 2007 Jun 8;369(3):794-811. doi: 10.1016/j.jmb.2007.03.061. Epub 2007 Mar 30. J Mol Biol. 2007. PMID: 17451745 Free PMC article.

4

Structural studies of pterin-based inhibitors of dihydropteroate synthase.

Hevener KE, Yun MK, Qi J, Kerr ID, Babaoglu K, Hurdle JG, Balakrishna K, White SW, Lee RE. Hevener KE, et al. Among authors: yun mk. J Med Chem. 2010 Jan 14;53(1):166-77. doi: 10.1021/jm900861d. J Med Chem. 2010. PMID: 19899766 Free PMC article.

5

Modulation of pantothenate kinase 3 activity by small molecules that interact with the substrate/allosteric regulatory domain.

Leonardi R, Zhang YM, Yun MK, Zhou R, Zeng FY, Lin W, Cui J, Chen T, Rock CO, White SW, Jackowski S. Leonardi R, et al. Among authors: yun mk. Chem Biol. 2010 Aug 27;17(8):892-902. doi: 10.1016/j.chembiol.2010.06.006. Chem Biol. 2010. PMID: 20797618 Free PMC article.

6

Synthesis of bi-substrate state mimics of dihydropteroate synthase as potential inhibitors and molecular probes.

Qi J, Virga KG, Das S, Zhao Y, Yun MK, White SW, Lee RE. Qi J, et al. Among authors: yun mk. Bioorg Med Chem. 2011 Feb 1;19(3):1298-305. doi: 10.1016/j.bmc.2010.12.003. Epub 2010 Dec 15. Bioorg Med Chem. 2011. PMID: 21216602 Free PMC article.

7

Development of a pterin-based fluorescent probe for screening dihydropteroate synthase.

Zhao Y, Hammoudeh D, Lin W, Das S, Yun MK, Li Z, Griffith E, Chen T, White SW, Lee RE. Zhao Y, et al. Among authors: yun mk. Bioconjug Chem. 2011 Oct 19;22(10):2110-7. doi: 10.1021/bc200346e. Epub 2011 Sep 30. Bioconjug Chem. 2011. PMID: 21916405 Free PMC article.

8

Catalysis and sulfa drug resistance in dihydropteroate synthase.

Yun MK, Wu Y, Li Z, Zhao Y, Waddell MB, Ferreira AM, Lee RE, Bashford D, White SW. Yun MK, et al. Science. 2012 Mar 2;335(6072):1110-4. doi: 10.1126/science.1214641. Science. 2012. PMID: 22383850 Free PMC article.

9

Structure-based design of novel pyrimido[4,5-c]pyridazine derivatives as dihydropteroate synthase inhibitors with increased affinity.

Zhao Y, Hammoudeh D, Yun MK, Qi J, White SW, Lee RE. Zhao Y, et al. Among authors: yun mk. ChemMedChem. 2012 May;7(5):861-70. doi: 10.1002/cmdc.201200049. Epub 2012 Mar 13. ChemMedChem. 2012. PMID: 22416048 Free PMC article.

10

The T4 phage SF1B helicase Dda is structurally optimized to perform DNA strand separation.

He X, Byrd AK, Yun MK, Pemble CW 4th, Harrison D, Yeruva L, Dahl C, Kreuzer KN, Raney KD, White SW. He X, et al. Among authors: yun mk. Structure. 2012 Jul 3;20(7):1189-200. doi: 10.1016/j.str.2012.04.013. Epub 2012 May 31. Structure. 2012. PMID: 22658750 Free PMC article.

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