Settleman J - Search Results

1

EGFR-mediated chromatin condensation protects KRAS-mutant cancer cells against ionizing radiation.

Wang M, Kern AM, Hülskötter M, Greninger P, Singh A, Pan Y, Chowdhury D, Krause M, Baumann M, Benes CH, Efstathiou JA, Settleman J, Willers H. Wang M, et al. Among authors: settleman j. Cancer Res. 2014 May 15;74(10):2825-34. doi: 10.1158/0008-5472.CAN-13-3157. Epub 2014 Mar 19. Cancer Res. 2014. PMID: 24648348 Free PMC article.

2

Specific biochemical inactivation of oncogenic Ras proteins by nucleoside diphosphate kinase.

Fischbach MA, Settleman J. Fischbach MA, et al. Among authors: settleman j. Cancer Res. 2003 Jul 15;63(14):4089-94. Cancer Res. 2003. PMID: 12874011

3

Inherited susceptibility to lung cancer may be associated with the T790M drug resistance mutation in EGFR.

Bell DW, Gore I, Okimoto RA, Godin-Heymann N, Sordella R, Mulloy R, Sharma SV, Brannigan BW, Mohapatra G, Settleman J, Haber DA. Bell DW, et al. Among authors: settleman j. Nat Genet. 2005 Dec;37(12):1315-6. doi: 10.1038/ng1671. Epub 2005 Oct 30. Nat Genet. 2005. PMID: 16258541

4

Epidermal growth factor receptor kinase domain mutations in esophageal and pancreatic adenocarcinomas.

Kwak EL, Jankowski J, Thayer SP, Lauwers GY, Brannigan BW, Harris PL, Okimoto RA, Haserlat SM, Driscoll DR, Ferry D, Muir B, Settleman J, Fuchs CS, Kulke MH, Ryan DP, Clark JW, Sgroi DC, Haber DA, Bell DW. Kwak EL, et al. Among authors: settleman j. Clin Cancer Res. 2006 Jul 15;12(14 Pt 1):4283-7. doi: 10.1158/1078-0432.CCR-06-0189. Clin Cancer Res. 2006. PMID: 16857803 Free PMC article.

5

Summary statement: novel agents in the treatment of lung cancer: advances in epidermal growth factor receptor-targeted agents.

Lynch TJ, Adjei AA, Bunn PA Jr, Eisen TG, Engelman J, Goss GD, Haber DA, Heymach JV, Jänne PA, Johnson BE, Johnson DH, Lilenbaum RC, Meyerson M, Sandler AB, Sequist LV, Settleman J, Wong KK, Hart CS. Lynch TJ, et al. Among authors: settleman j. Clin Cancer Res. 2006 Jul 15;12(14 Pt 2):4365s-4371s. doi: 10.1158/1078-0432.CCR-06-1005. Clin Cancer Res. 2006. PMID: 16857812 No abstract available.

6

"Oncogenic shock": explaining oncogene addiction through differential signal attenuation.

Sharma SV, Fischbach MA, Haber DA, Settleman J. Sharma SV, et al. Among authors: settleman j. Clin Cancer Res. 2006 Jul 15;12(14 Pt 2):4392s-4395s. doi: 10.1158/1078-0432.CCR-06-0096. Clin Cancer Res. 2006. PMID: 16857816 Review.

7

Molecular targeted therapy of lung cancer: EGFR mutations and response to EGFR inhibitors.

Haber DA, Bell DW, Sordella R, Kwak EL, Godin-Heymann N, Sharma SV, Lynch TJ, Settleman J. Haber DA, et al. Among authors: settleman j. Cold Spring Harb Symp Quant Biol. 2005;70:419-26. doi: 10.1101/sqb.2005.70.043. Cold Spring Harb Symp Quant Biol. 2005. PMID: 16869779 Review.

8

Epidermal growth factor receptor mutations in lung cancer.

Sharma SV, Bell DW, Settleman J, Haber DA. Sharma SV, et al. Among authors: settleman j. Nat Rev Cancer. 2007 Mar;7(3):169-81. doi: 10.1038/nrc2088. Nat Rev Cancer. 2007. PMID: 17318210 Review.

9

Epidermal growth factor receptor mutants from human lung cancers exhibit enhanced catalytic activity and increased sensitivity to gefitinib.

Mulloy R, Ferrand A, Kim Y, Sordella R, Bell DW, Haber DA, Anderson KS, Settleman J. Mulloy R, et al. Among authors: settleman j. Cancer Res. 2007 Mar 1;67(5):2325-30. doi: 10.1158/0008-5472.CAN-06-4293. Cancer Res. 2007. PMID: 17332364

10

Drugging the bad "AKT-TOR" to overcome TKI-resistant lung cancer.

Settleman J, Kurie JM. Settleman J, et al. Cancer Cell. 2007 Jul;12(1):6-8. doi: 10.1016/j.ccr.2007.06.010. Cancer Cell. 2007. PMID: 17613432 Free article. Review.

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